Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 3/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.41 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | PTAFR | P25105 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 3/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ACE | P12821 | 2/20 | 0.38 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3486703 | 0.94 | NOTUM (0.63) | NOTUMKMT2AMAPTTAAR1HRH3 | |
| SCHEMBL23360751 | 0.83 | NOTUM (0.43) | NOTUMKMT2AMAPTTAAR1MEN1 | |
| SCHEMBL17005756 | 0.83 | MEN1 (0.44) | NOTUMKMT2ATAAR1MEN1ALDH1A1 | |
| SCHEMBL3996959 | 0.80 | DPP8 (0.44) | NOTUMKMT2AMAPTTAAR1MEN1 | |
| SCHEMBL952264 | 0.80 | ESR1 (0.59) | NOTUMKMT2AMAPTTAAR1MEN1 | |
| SCHEMBL2075762 | 0.79 | NOTUM (0.44) | NOTUMKMT2AMAPTTAAR1MEN1 | |
| SCHEMBL3210469 | 0.78 | NOTUM (1.00) | NOTUMKMT2AMAPTTAAR1HRH3 | |
| SCHEMBL30539318 | 0.78 | NOTUM (1.00) | NOTUMKMT2AMAPTTAAR1HRH3 | |
| SCHEMBL18351760 | 0.77 | HPGD (0.51) | KMT2AMAPTALDH1A1CYP3A4CYP2C9 | |
| SCHEMBL18351817 | 0.76 | HPGD (0.52) | ALDH1A1CYP3A4CYP2C9HPGDCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | claimed |
| US-6043254-A | ANTIPROLIFERATIVE AGENT; ENZYME INHIBITOR | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-03-28 | — | — | US | disclosed |