Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NOTUM | Q6P988 | 2/20 | 0.43 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 4/20 | 0.41 |
| ▸ | RAB9A | P51151 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | ABHD6 | Q9BV23 | 1/20 | 0.41 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.40 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.40 |
| ▸ | TAS1R2 | Q8TE23 | 2/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 3/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.38 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8013063 | 0.83 | NOTUM (0.63) | NOTUMNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL1202085 | 0.80 | ALDH1A1 (0.48) | NOTUMSMN1; SMN2ESR2KMT2AMEN1 | |
| SCHEMBL30056523 | 0.80 | NOTUM (0.67) | NOTUMNPC1RAB9ASMN1; SMN2ABHD6 | |
| SCHEMBL464005 | 0.80 | NOTUM (0.67) | NOTUMNPC1RAB9ASMN1; SMN2ABHD6 | |
| SCHEMBL17005756 | 0.79 | MEN1 (0.44) | NOTUMNPC1RAB9ASMN1; SMN2TAAR1 | |
| SCHEMBL952312 | 0.79 | ESR2 (0.62) | NR1H2SMN1; SMN2ABHD6ESR2MAPT | |
| SCHEMBL1202119 | 0.79 | ABHD6 (0.47) | NOTUMNR1H2ABHD6ESR2PRMT5 | |
| SCHEMBL6097273 | 0.77 | NOTUM (0.58) | NOTUMNPC1RAB9ASMN1; SMN2ABHD6 | |
| SCHEMBL3486703 | 0.77 | NOTUM (0.63) | NOTUMNPC1RAB9ASMN1; SMN2TAS1R3 | |
| SCHEMBL1201231 | 0.77 | PRMT5 (0.41) | NOTUMSMN1; SMN2ABHD6ESR2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3752492-B1 | FUNGICIDAL OXADIAZOLES | BAYER AG (DE) | 2022-12-21 | — | — | EP | disclosed |
| US-20210147371-A1 | OXADIAZOLINE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 2021-05-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210147371-A1 | OXADIAZOLINE DERIVATIVES | DDT, FOXO3, PDCD4 | NOTUM 292/4885NR1H2 3799/4885NPC1 3922/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.