Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2B | P29275 | 8/20 | 0.68 |
| ▸ | TNF | P01375 | 3/20 | 0.68 |
| ▸ | PDE4A | P27815 | 2/20 | 0.68 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.68 |
| ▸ | PDE4C | Q08493 | 2/20 | 0.68 |
| ▸ | PDE4D | Q08499 | 2/20 | 0.68 |
| ▸ | ACHE | P22303 | 2/20 | 0.68 |
| ▸ | USP2 | O75604 | 1/20 | 0.68 |
| ▸ | LMNA | P02545 | 1/20 | 0.68 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.68 |
| ▸ | TSHR | P16473 | 1/20 | 0.68 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.68 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.68 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.68 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.68 |
| ▸ | CHIT1 | Q13231 | 1/20 | 0.62 |
| ▸ | CHIA | Q9BZP6 | 1/20 | 0.62 |
| ▸ | GLA | P06280 | 1/20 | 0.59 |
| ▸ | BLM | P54132 | 1/20 | 0.59 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316168 | 1.00 | ADORA2B (0.68) | ADORA2BTNFPDE4APDE4BPDE4C | |
| SCHEMBL7315268 | 1.00 | ADORA2B (0.68) | ADORA2BTNFPDE4APDE4BPDE4C | |
| SCHEMBL7305272 | 0.99 | ADORA2B (0.70) | ADORA2BTNFPDE4APDE4BPDE4C | |
| SCHEMBL7315040 | 0.94 | ADORA2B (0.67) | ADORA2BTNFPDE4APDE4BPDE4C | |
| SCHEMBL16120981 | 0.93 | ADORA2B (0.77) | ADORA2BTNFPDE4APDE4BPDE4C | |
| Bisdionin D SCHEMBL16120988 | 0.91 | ADORA2B (0.79) | ADORA2BTNFPDE4APDE4BPDE4C | |
| SCHEMBL7320105 | 0.88 | ADORA2B (0.67) | ADORA2BTNFPDE4APDE4BPDE4C | |
| Bisdionin C SCHEMBL10018600 | 0.88 | CHIT1 (0.75) | ADORA2BTNFPDE4APDE4BPDE4C | |
| SCHEMBL23144749 | 0.87 | PDE4A (0.70) | ADORA2BTNFPDE4APDE4BPDE4C | |
| Pentifylline SCHEMBL147256 | 0.87 | PDE4A (0.70) | ADORA2BTNFPDE4APDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670506-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, MICROBIOCIDES | CELL THERAPEUTICS, INC. (US) | 1997-09-23 | — | — | US | claimed |
| US-6020337-A | Electronegative-substituted long chain xanthine compounds | CELL THERAPEUTICS, INC. (US) | 2000-02-01 | — | — | US | disclosed |
| US-5670506-A | ANTIINFLAMMATORY AGENTS, FUNGICIDES, MICROBIOCIDES | CELL THERAPEUTICS, INC. (US) | 1997-09-23 | — | — | US | disclosed |
| EP-0714302-A4 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS INC (US) | 1996-10-09 | — | — | EP | disclosed |
| EP-0714302-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1996-06-05 | — | — | EP | disclosed |
| WO-1994022449-A1 | THERAPEUTIC COMPOUNDS | CELL THERAPEUTICS, INC. (US) | 1994-10-13 | — | — | WO | disclosed |
| US-4576947-A | HYDROXYALKYLXANTHINES, INCREASING CEREBRAL BLOOD FLOW, BRONCHODILATORS | HOECHST AKTIENGESELLSCHAFT (DE) | 1986-03-18 | — | — | US | disclosed |
| US-4515795-A | INSUFFICIENCY OF CEREBRAL BLOOD FLOW | HOECHST AKTIENGESELLSCHAFT (DE) | 1985-05-07 | — | — | US | disclosed |