E968

E968

SCHEMBL8013603

O=C(O)C(S)(S)C(S)S.OCC(CO)(CO)CO.OCC(O)C(O)CO

nearest known ligand 0.35

Full drug profile on Sugi Atlas →

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.32
LMNA P02545 1/20 0.31
USP2 O75604 1/20 0.31
SLCO1B1 Q9Y6L6 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E968 SCHEMBL3683173 0.92 PDE4A (0.37) PDE4ALMNAUSP2SLCO1B1
SCHEMBL136616 0.90 FOLH1 (0.30)
SCHEMBL10595313 0.90 FOLH1 (0.30)
SCHEMBL28846605 0.77
Acetoacetic Acid SCHEMBL8981493 0.77 KDM4E (0.31)
SCHEMBL1471055 0.76
E968 SCHEMBL23467010 0.75 PDE4A (0.37) PDE4ALMNAUSP2SLCO1B1
E968 SCHEMBL5923897 0.73 LMNA (0.47) PDE4ALMNA
E968 SCHEMBL2138801 0.73 LMNA (0.47) PDE4ALMNA
SCHEMBL2202864 0.69 FOLH1 (0.44) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6019915-A PHOTOCURING A MIXTURE OF A THIOURETHANE POLYMER FROM A POLYTHIOL HAVING AT LEAST 3 MERCAPTO GROUPS AND AN INTRAMOLECULAR SULFIDE BOND AND POLYISOCYANATE, POLY(METH)ACRYLATE AND AN UNSATURATED COMPOUND MITSUI CHEMICALS, INC. (JP) 2000-02-01 US disclosed