E968

E968

SCHEMBL3683173

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nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
PDE4A P27815 1/20 0.37
LMNA P02545 2/20 0.34
USP2 O75604 1/20 0.34
SLCO1B1 Q9Y6L6 1/20 0.34
OR51E2 Q9H255 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.32
TDP1 Q9NUW8 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
E968 SCHEMBL8013603 0.92 PDE4A (0.32) PDE4ALMNAUSP2SLCO1B1
SCHEMBL1471055 0.83
SCHEMBL10595313 0.79 FOLH1 (0.30)
SCHEMBL136616 0.79 FOLH1 (0.30)
SCHEMBL5504748 0.73 OR51E2 (0.38) PDE4ALMNAOR51E2
E968 SCHEMBL29466723 0.71 PDE4A (0.52) PDE4ALMNAUSP2SLCO1B1OR51E2
E968 SCHEMBL28674303 0.71 PDE4A (0.52) PDE4ALMNAUSP2SLCO1B1OR51E2
E968 SCHEMBL28441780 0.68 PDE4A (0.50) PDE4ALMNAUSP2SLCO1B1OR51E2
E968 SCHEMBL9858617 0.67 PDE4A (0.44) PDE4ALMNAUSP2SLCO1B1OR51E2
Glycerin SCHEMBL136507 0.67 LMNA (0.53) PDE4ALMNAUSP2SLCO1B1OR51E2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20100069548-A1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITIONS DSM IP ASSETS B.V. (NL) 2010-03-18 US disclosed
EP-2038316-B1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITIONS DSM IP ASSETS BV (NL) 2009-12-30 EP disclosed
EP-2038316-A1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITIONS DSMIP Assets B.V. (NL) 2009-03-25 EP disclosed
WO-2008003496-A1 UNSATURATED POLYESTER RESIN OR VINYL ESTER RESIN COMPOSITIONS DSM IP ASSETS B.V. (NL) 2008-01-10 WO disclosed