SCHEMBL8014113

SCHEMBL8014113

CCCCCCCC/C=C\CCCCCCCC(=O)OCC(CNC(=O)OCCN(C)C)OC(=O)CCCCCCC/C=C\CCCCCCCC

nearest known ligand 0.60

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 3/20 0.60
PRKCE Q02156 2/20 0.60
PRKCQ Q04759 2/20 0.60
PRKCD Q05655 2/20 0.60
DNM1 Q05193 1/20 0.52
ALDH1A1 P00352 1/20 0.52
LMNA P02545 1/20 0.52
ENPP2 Q13822 2/20 0.48
DGKA P23743 1/20 0.48
RECQL P46063 1/20 0.47
BLM P54132 1/20 0.47
TDP1 Q9NUW8 1/20 0.47
LPAR3 Q9UBY5 1/20 0.47
SELP P16109 1/20 0.47
LPAR1 Q92633 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8021318 1.00 PRKCA (0.60) PRKCAPRKCEPRKCQPRKCDDNM1
SCHEMBL8021321 1.00 PRKCA (0.60) PRKCAPRKCEPRKCQPRKCDDNM1
SCHEMBL8005139 1.00 PRKCA (0.60) PRKCAPRKCEPRKCQPRKCDDNM1
SCHEMBL8014046 0.95 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8014051 0.95 PRKCA (0.59) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8014407 0.94 PRKCA (0.58) PRKCAPRKCEPRKCQPRKCDALDH1A1
SCHEMBL8016333 0.94 DNM1 (0.59) PRKCAPRKCEPRKCQPRKCDDNM1
SCHEMBL8013834 0.94 DNM1 (0.59) PRKCAPRKCEPRKCQPRKCDDNM1
SCHEMBL8018279 0.94 DNM1 (0.59) PRKCAPRKCEPRKCQPRKCDDNM1
SCHEMBL8016850 0.93 PRKCA (0.51) PRKCAPRKCEPRKCQPRKCDDNM1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
EP-0685457-B1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU CO LTD (JP) 1999-12-15 EP disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed