Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.44 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.44 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19538828 | 0.83 | BRD4 (0.46) | BRD4CREBBPDGAT1 | |
| SCHEMBL189854 | 0.82 | BRD4 (0.46) | BRD4CREBBPDGAT1 | |
| SCHEMBL29868688 | 0.82 | BRD4 (0.46) | BRD4CREBBPDGAT1 | |
| SCHEMBL29224192 | 0.81 | HDAC1 (0.38) | BRD4CREBBPDGAT1 | |
| SCHEMBL19531663 | 0.80 | BRD4 (0.44) | BRD4CREBBPDGAT1 | |
| SCHEMBL30280199 | 0.79 | BRD4 (0.33) | BRD4CREBBPDGAT1 | |
| SCHEMBL23256916 | 0.79 | DGAT1 (0.33) | DGAT1 | |
| SCHEMBL29224509 | 0.79 | BRD4 (0.36) | BRD4CREBBPDGAT1 | |
| SCHEMBL17457845 | 0.79 | BRD4 (0.44) | BRD4CREBBPDGAT1 | |
| SCHEMBL8028228 | 0.78 | BRD4 (0.43) | BRD4CREBBPDGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6110931-A | FOR PREGNANCY PROPHYLAXIS AND TREATMENT OF GLANDULAR DISORDERS, HORMONE DEFICIENCY DISORDERS, GASTROINTESTINAL DISORDERS, GROWTH DISORDERS | MERCK & CO., INC. (US) | 2000-08-29 | — | — | US | disclosed |
| US-6025366-A | Antagonists of gonadotropin releasing hormone | MERCK & CO., INC. (US) | 2000-02-15 | — | — | US | disclosed |