Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | JAK1 | P23458 | 6/20 | 0.37 |
| ▸ | JAK3 | P52333 | 6/20 | 0.37 |
| ▸ | JAK2 | O60674 | 5/20 | 0.37 |
| ▸ | TYK2 | P29597 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 2/20 | 0.34 |
| ▸ | F2 | P00734 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | GLA | P06280 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | CCKBR | P32239 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7374222 | 0.86 | TP53 (0.39) | ALDH1A1KDM4EJAK1JAK3JAK2 | |
| SCHEMBL3238629 | 0.71 | F2 (0.46) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL7409106 | 0.70 | MEN1 (0.41) | ALDH1A1KDM4EMEN1KMT2APOLB | |
| SCHEMBL8010575 | 0.69 | GAA (0.42) | ALDH1A1JAK1JAK3JAK2TYK2 | |
| SCHEMBL7410701 | 0.68 | TP53 (0.37) | ALDH1A1JAK1JAK3JAK2TYK2 | |
| SCHEMBL23460591 | 0.65 | KDM4E (0.43) | ALDH1A1KDM4EPOLBF2 | |
| SCHEMBL7220914 | 0.65 | MEN1 (0.48) | ALDH1A1KDM4EMEN1KMT2AF2 | |
| SCHEMBL948953 | 0.64 | ALDH1A1 (0.51) | ALDH1A1MEN1KMT2APOLBGAA | |
| SCHEMBL23461186 | 0.64 | F2 (0.49) | ALDH1A1KDM4EF2 | |
| SCHEMBL23461141 | 0.64 | KDM4E (0.46) | ALDH1A1KDM4EJAK1JAK3JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6147078-A | SERINE PROTEASE INHIBITOR | MERCK & CO., INC. (US) | 2000-11-14 | — | — | US | disclosed |