SCHEMBL8014369

SCHEMBL8014369

CCCCCCCCC=CCCCCCCCCOCC(COCCCCCCCCC=CCCCCCCCC)OC(=O)CCCN1CCOCC1

nearest known ligand 0.59

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 3/20 0.49
PRKCA P17252 2/20 0.49
PRKCE Q02156 1/20 0.49
PRKCQ Q04759 1/20 0.49
PRKCD Q05655 1/20 0.49
DAGLA Q9Y4D2 2/20 0.48
TLR2 O60603 1/20 0.47
FAAH O00519 1/20 0.46
MAPT P10636 1/20 0.46
HPGD P15428 1/20 0.46
CNR1 P21554 1/20 0.46
CNR2 P34972 1/20 0.46
LPAR1 Q92633 1/20 0.45
THRB P10828 2/20 0.44
THRA P10827 1/20 0.44
S1PR1 P21453 1/20 0.43
SLC6A5 Q9Y345 1/20 0.43
LMNA P02545 1/20 0.43
DGKA P23743 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8014365 1.00 ALDH1A1 (0.49) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL8153765 0.91 PRKCA (0.51) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL8153767 0.91 PRKCA (0.51) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL8004914 0.90 ALDH1A1 (0.50) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL8014242 0.90 ALDH1A1 (0.50) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL8014244 0.90 ALDH1A1 (0.50) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL8004917 0.90 ALDH1A1 (0.50) ALDH1A1PRKCAPRKCEPRKCQPRKCD
SCHEMBL8012809 0.89 PRKCA (0.50) PRKCAPRKCEPRKCQPRKCDTLR2
SCHEMBL8012805 0.89 PRKCA (0.50) PRKCAPRKCEPRKCQPRKCDTLR2
SCHEMBL8014160 0.84 TLR2 (0.47) TLR2CNR2THRBTHRA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0685234-B1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU CO LTD (JP) 2000-05-10 EP disclosed
US-6020317-A Glycerol derivative, device and pharmaceutical composition NIPPON SHINYAKU CO. LTD. (JP) 2000-02-01 US disclosed
US-5705188-A LIPID MIXTURE, ANTITUMOR AGENTS NIPPON SHINYAKU COMPANY, LTD. (JP) 1998-01-06 US disclosed
EP-0685457-A1 GLYCEROL DERIVATIVE, DEVICE AND PHARMACEUTICAL COMPOSITION NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed
EP-0685234-A1 DRUG COMPOSITION CONTAINING NUCLEIC ACID COPOLYMER NIPPON SHINYAKU COMPANY, LIMITED (JP) 1995-12-06 EP disclosed