SCHEMBL801437

SCHEMBL801437

COCC[C@H]1CN(C2=Nc3ccc(F)cc3Nc3sc(C)cc32)CCN1C

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHRM1 P11229 5/20 0.52
HRH1 P35367 5/20 0.52
CHRM2 P08172 4/20 0.52
CHRM4 P08173 4/20 0.52
CHRM5 P08912 4/20 0.52
DRD2 P14416 4/20 0.52
CHRM3 P20309 4/20 0.52
DRD1 P21728 4/20 0.52
ADRA1D P25100 4/20 0.52
HTR2A P28223 4/20 0.52
HTR2C P28335 4/20 0.52
ADRA1A P35348 4/20 0.52
ADRA1B P35368 4/20 0.52
HTR2B P41595 4/20 0.52
ADRA2A P08913 3/20 0.52
ADRA2B P18089 3/20 0.52
ADRA2C P18825 3/20 0.52
KCNH2 Q12809 3/20 0.52
HTR3E A5X5Y0 1/20 0.52
MEN1 O00255 1/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4835702 1.00 CHRM1 (0.52) CHRM1HRH1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL4844972 0.99 CHRM1 (0.51) CHRM1HRH1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL4844964 0.99 CHRM1 (0.51) CHRM1HRH1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL4843486 0.99 CHRM1 (0.51) CHRM1HRH1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL4843504 0.99 CHRM1 (0.51) CHRM1HRH1CHRM2CHRM4CHRM5
SCHEMBL4844033 0.95 CHRM1 (0.50) CHRM1HRH1CHRM2CHRM4CHRM5
SCHEMBL4844017 0.95 CHRM1 (0.50) CHRM1HRH1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL4838588 0.94 CHRM1 (0.49) CHRM1HRH1CHRM2CHRM4CHRM5
Hydrochloric Acid SCHEMBL4838580 0.94 CHRM1 (0.49) CHRM1HRH1CHRM2CHRM4CHRM5
SCHEMBL14156742 0.94 CHRM1 (0.50) CHRM1HRH1CHRM2CHRM4CHRM5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113670367-B Millimeter wave and ultrasonic sensor 霍尼韦尔国际公司 2024-12-20 CN claimed
EP-3910328-B1 MILLIMETER-WAVE AND ULTRASOUND SENSORS FOR FLUID MIXTURE PARAMETER DETERMINATION HONEYWELL INT INC (US) 2023-11-29 EP claimed
US-7384934-B2 Piperazine substituted aryl benzodiazepines ELI LILLY AND COMPANY (US) 2008-06-10 US claimed
EP-1546134-A1 PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES ELI LILLY AND COMPANY (US) 2005-06-29 EP claimed
WO-2004014895-A1 PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES ELI LILLY AND COMPANY (US) 2004-02-19 WO claimed
US-12575756-B2 Magnetic resonance imaging apparatus, phase correcting method, and imaging controlling method CANON MEDICAL SYSTEMS CORPORATION (JP) 2026-03-17 US disclosed
CN-116273141-B Supported catalyst for preparing ketone by cyclododecanol dehydrogenation, preparation method and application thereof 万华化学集团股份有限公司 2025-06-03 CN disclosed
CN-111833790-B Display device and driving method thereof 三星显示有限公司 2025-02-28 CN disclosed
CN-113670367-B Millimeter wave and ultrasonic sensor 霍尼韦尔国际公司 2024-12-20 CN disclosed
CN-113670367-B Millimeter wave and ultrasonic sensor 霍尼韦尔国际公司 2024-12-20 CN disclosed
US-20230397835-A1 MAGNETIC RESONANCE IMAGING APPARATUS, PHASE CORRECTING METHOD, AND IMAGING CONTROLLING METHOD CANON MEDICAL SYSTEMS CORPORATION (JP) 2023-12-14 US disclosed
US-11711618-B2 Image processing apparatus, image processing method, and program Sony Group Corporation 2023-07-25 US disclosed
US-7384934-B2 Piperazine substituted aryl benzodiazepines ELI LILLY AND COMPANY (US) 2008-06-10 US disclosed
US-7384934-B2 Piperazine substituted aryl benzodiazepines ELI LILLY AND COMPANY (US) 2008-06-10 US disclosed
US-7384934-B2 Piperazine substituted aryl benzodiazepines ELI LILLY AND COMPANY (US) 2008-06-10 US disclosed
EP-1546134-B1 PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES LILLY CO ELI (US) 2007-05-02 EP disclosed
EP-1546134-B1 PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES LILLY CO ELI (US) 2007-05-02 EP disclosed
US-20060084643-A1 Piperazine substituted aryl benzodiazepines ELI LILLY AND COMPANY 2006-04-20 US disclosed
EP-1546134-A1 PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES ELI LILLY AND COMPANY (US) 2005-06-29 EP disclosed
WO-2004014895-A1 PIPERAZINE SUBSTITUTED ARYL BENZODIAZEPINES ELI LILLY AND COMPANY (US) 2004-02-19 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12575756-B2 Magnetic resonance imaging apparatus, phase correcting method, and imaging controlling method RAD1, RXFP1, MRE11 CHRM1 588/4885HRH1 3347/4885CHRM2 436/4885
US-20060084643-A1 Piperazine substituted aryl benzodiazepines GABBR1, GABBR2, GABRA5 CHRM1 302/4885HRH1 570/4885CHRM2 347/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.