SCHEMBL8014486

SCHEMBL8014486

C=C(C)C(=O)NC(CC)(NC(=O)C(=C)C)N(C)C

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10814792 0.74 TGFBR1 (0.36) TGFBR1
SCHEMBL27975590 0.72 TGFBR1 (0.35) TGFBR1
SCHEMBL18709152 0.72 TGFBR1 (0.35) TGFBR1
SCHEMBL9805999 0.72 EPHX1 (0.40) TGFBR1
SCHEMBL17350285 0.71 TGFBR1 (0.34) TGFBR1
SCHEMBL4828403 0.71 TDP1 (0.35) TGFBR1
SCHEMBL17704123 0.71 ALDH1A1 (0.30)
SCHEMBL28937708 0.69 TGFBR1 (0.33) TGFBR1
SCHEMBL5822721 0.69 TGFBR1 (0.33) TGFBR1
SCHEMBL275365 0.69 TGFBR1 (0.37) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807151-B1 POLYMERIC EARTH SUPPORT FLUID COMPOSITIONS AND METHOD FOR THEIR USE KB TECHNOLOGIES LTD (US) 2000-08-16 EP claimed