SCHEMBL8014489

SCHEMBL8014489

C=C(C)C(=O)NC(CCN(C)C)NC(=O)C(=C)C

nearest known ligand 0.43

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.43
UTS2R Q9UKP6 6/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8974574 0.85 TGFBR1 (0.43) TGFBR1UTS2RHTR2AHRH1PAOX
Propane SCHEMBL28191962 0.81 TGFBR1 (0.41) TGFBR1
SCHEMBL29020061 0.81 TGFBR1 (0.41) TGFBR1
SCHEMBL27709125 0.81 TGFBR1 (0.44) TGFBR1UTS2R
SCHEMBL20819796 0.79 TGFBR1 (0.48) TGFBR1
SCHEMBL10909470 0.78 TGFBR1 (0.47) TGFBR1HTR2AHRH1
SCHEMBL6690649 0.76 TGFBR1 (0.37) TGFBR1
SCHEMBL8027863 0.75 TGFBR1 (0.42) TGFBR1UTS2RPAOX
SCHEMBL13205121 0.74 TGFBR1 (0.52) TGFBR1
Hydrochloric Acid SCHEMBL22089800 0.73 PLA2G2C (0.38) TGFBR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0807151-B1 POLYMERIC EARTH SUPPORT FLUID COMPOSITIONS AND METHOD FOR THEIR USE KB TECHNOLOGIES LTD (US) 2000-08-16 EP claimed