SCHEMBL8974574

SCHEMBL8974574

C=C(C)C(=O)NC(C)CCN(C)C

nearest known ligand 0.43

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TGFBR1 P36897 1/20 0.43
RXFP1 Q9HBX9 1/20 0.33
SMN1; SMN2 Q16637 2/20 0.31
ALDH1A1 P00352 1/20 0.31
NPC1 O15118 1/20 0.31
RAB9A P51151 1/20 0.31
UTS2R Q9UKP6 4/20 0.31
TSHR P16473 1/20 0.31
HTR2A P28223 1/20 0.31
HRH1 P35367 1/20 0.31
USP2 O75604 1/20 0.30
PAOX Q6QHF9 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propane SCHEMBL28191962 0.96 TGFBR1 (0.41) TGFBR1RXFP1SMN1; SMN2
SCHEMBL28197376 0.85 TGFBR1 (0.44) TGFBR1RXFP1
SCHEMBL8014489 0.85 TGFBR1 (0.43) TGFBR1UTS2RHTR2AHRH1PAOX
SCHEMBL28191959 0.83 TGFBR1 (0.35) TGFBR1
SCHEMBL13780653 0.82 ACACB (0.37) ALDH1A1TSHR
SCHEMBL29020061 0.81 TGFBR1 (0.41) TGFBR1
SCHEMBL27709125 0.81 TGFBR1 (0.44) TGFBR1UTS2R
SCHEMBL4037645 0.80 TGFBR1 (0.46) TGFBR1RXFP1ALDH1A1TSHR
SCHEMBL472264 0.80 TGFBR1 (0.46) TGFBR1RXFP1SMN1; SMN2ALDH1A1NPC1
SCHEMBL29519156 0.80 TGFBR1 (0.50) TGFBR1RXFP1SMN1; SMN2ALDH1A1NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5294691-A Absorbing an aqueous soution of the copolymer having amide, nitrile, carboxylic acid or sulfonic acid functionalities PHILLIPS PETROLEUM COMPANY (US) 1994-03-15 US claimed
US-5250642-A High absorbency to aqueous electrolyte solutions PHILLIPS PETROLEUM COMPANY (US) 1993-10-05 US claimed
US-5523367-A DISPOSABLE PRODUCTS PHILLIPS PETROLEUM COMPANY (US) 1996-06-04 US disclosed
US-5484865-A Copolymers of ampholytic ion pairs containing vinylic tertiary amine PHILLIPS PETROLEUM COMPANY (US) 1996-01-16 US disclosed
US-5294691-A Absorbing an aqueous soution of the copolymer having amide, nitrile, carboxylic acid or sulfonic acid functionalities PHILLIPS PETROLEUM COMPANY (US) 1994-03-15 US disclosed
US-5250642-A High absorbency to aqueous electrolyte solutions PHILLIPS PETROLEUM COMPANY (US) 1993-10-05 US disclosed