Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | APP | P05067 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8014663 | 1.00 | ALDH1A1 (0.33) | ALDH1A1LMNAHSD17B10THRBFNTA | |
| SCHEMBL2721925 | 0.80 | FNTA (0.46) | ALDH1A1LMNAHSD17B10THRBFNTA | |
| SCHEMBL5164512 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10THRBFNTA | |
| SCHEMBL5616300 | 0.80 | ALDH1A1 (0.42) | ALDH1A1LMNAHSD17B10THRBFNTA | |
| SCHEMBL3388403 | 0.77 | FNTA (0.56) | ALDH1A1HSD17B10THRBFNTAFNTB | |
| SCHEMBL14900199 | 0.74 | CYP1A2 (0.55) | ALDH1A1LMNAHSD17B10CYP1A2 | |
| SCHEMBL3451347 | 0.74 | APP (0.38) | LMNATHRBFNTAFNTBPGGT1B | |
| SCHEMBL5014807 | 0.73 | CYP1A2 (0.53) | ALDH1A1LMNAHSD17B10CYP1A2 | |
| SCHEMBL126032 | 0.72 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10THRBFNTA | |
| SCHEMBL222774 | 0.72 | ALDH1A1 (0.46) | ALDH1A1LMNAHSD17B10THRBFNTA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0896600-B1 | NON-THROMBOGENIC AND ANTI-THROMBOGENIC POLYMERS | LUTHRA AJAY KUMAR (GB) | 2000-01-12 | — | — | EP | claimed |