SCHEMBL8014686

SCHEMBL8014686

CCCCCC([Si](OC)OC)[Si](C)(C)OC

nearest known ligand 0.31

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
OPRM1 P35372 1/20 0.31
ZDHHC7 Q9NXF8 1/20 0.31
CA1 P00915 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8019423 0.94
SCHEMBL8022693 0.86
SCHEMBL8014539 0.85 OPRM1 (0.31) OPRM1ZDHHC7CA1
SCHEMBL8015108 0.82 OPRM1 (0.32) OPRM1ZDHHC7CA1
SCHEMBL8015372 0.78
SCHEMBL8022259 0.77
SCHEMBL8014743 0.76 CA1 (0.31) CA1
SCHEMBL1821988 0.73 ZDHHC7 (0.39) OPRM1ZDHHC7CA1
SCHEMBL557305 0.71 ZDHHC7 (0.42) ZDHHC7
SCHEMBL6709890 0.71 ZDHHC7 (0.42) ZDHHC7

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0653472-B1 Curable organopolysiloxane composition containing adhesion promoter DOW CORNING TORAY SILICONE (JP) 2000-01-19 EP disclosed
US-5527932-A REACTION PRODUCT OF AMINE, UNSATURATED EPOXY COMPOUNDS AND SILICON COMPOUND WITH AT LEAST TWO SILICON-BONDED ALKOXY GROUPS DOW CORNING TORAY SILICONE CO., LTD. (JP) 1996-06-18 US disclosed
US-5445891-A A reaction product of an amine compound with an aliphatically unsaturated epoxy compound DOW CORNING TORAY SILICONCO., LTD. (JP) 1995-08-29 US disclosed
EP-0653472-A2 Curable organopolysiloxane composition containing adhesion promoter Dow Corning Toray Silicone Company, Limited (JP) 1995-05-17 EP disclosed