⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019423 | 0.88 | — | — | |
| SCHEMBL8014686 | 0.86 | OPRM1 (0.31) | — | |
| SCHEMBL8006224 | 0.83 | — | — | |
| SCHEMBL8022259 | 0.82 | — | — | |
| SCHEMBL8018041 | 0.80 | — | — | |
| SCHEMBL8015372 | 0.71 | — | — | |
| SCHEMBL8014539 | 0.69 | OPRM1 (0.31) | — | |
| SCHEMBL6711951 | 0.69 | CHRM1 (0.31) | — | |
| SCHEMBL8014743 | 0.68 | CA1 (0.31) | — | |
| SCHEMBL8015108 | 0.67 | OPRM1 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0653472-B1 | Curable organopolysiloxane composition containing adhesion promoter | DOW CORNING TORAY SILICONE (JP) | 2000-01-19 | — | — | EP | disclosed |
| US-5527932-A | REACTION PRODUCT OF AMINE, UNSATURATED EPOXY COMPOUNDS AND SILICON COMPOUND WITH AT LEAST TWO SILICON-BONDED ALKOXY GROUPS | DOW CORNING TORAY SILICONE CO., LTD. (JP) | 1996-06-18 | — | — | US | disclosed |
| US-5445891-A | A reaction product of an amine compound with an aliphatically unsaturated epoxy compound | DOW CORNING TORAY SILICONCO., LTD. (JP) | 1995-08-29 | — | — | US | disclosed |
| EP-0653472-A2 | Curable organopolysiloxane composition containing adhesion promoter | Dow Corning Toray Silicone Company, Limited (JP) | 1995-05-17 | — | — | EP | disclosed |