Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | KCNQ3 | O43525 | 1/20 | 0.33 |
| ▸ | KCNQ2 | O43526 | 1/20 | 0.33 |
| ▸ | KCNQ4 | P56696 | 1/20 | 0.33 |
| ▸ | KCNQ5 | Q9NR82 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8703672 | 0.87 | CYP3A4 (0.32) | — | |
| SCHEMBL8704125 | 0.85 | CA1 (0.34) | CA1CA2POLBKDM4EMAPT | |
| SCHEMBL8021762 | 0.85 | CA1 (0.42) | CA1CA2KCNQ3KCNQ2KCNQ4 | |
| SCHEMBL8022822 | 0.82 | POLB (0.33) | KCNQ3KCNQ2KCNQ4KCNQ5GRIK2 | |
| SCHEMBL8017376 | 0.80 | KDM4E (0.39) | KCNQ3KCNQ2KCNQ4KCNQ5GRIK2 | |
| SCHEMBL8019205 | 0.80 | HRH3 (0.35) | KCNQ3KCNQ2KCNQ4KCNQ5GRIK2 | |
| Bicarbonate SCHEMBL8015454 | 0.78 | KDM4E (0.35) | KCNQ3KCNQ2KCNQ4KCNQ5POLB | |
| SCHEMBL8015735 | 0.78 | TAS1R3 (0.36) | KCNQ3KCNQ2KCNQ4KCNQ5GRIK2 | |
| SCHEMBL8022780 | 0.78 | — | — | |
| SCHEMBL8015581 | 0.77 | P2RX7 (0.32) | CA1CA2KCNQ3KCNQ2KCNQ4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773920-B1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| US-5808135-A | HERBICIDE; PESTICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0773920-A1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003366-A1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |