Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RXRA | P19793 | 16/20 | 0.69 |
| ▸ | RXRG | P48443 | 11/20 | 0.69 |
| ▸ | RARB | P10826 | 4/20 | 0.69 |
| ▸ | RARG | P13631 | 4/20 | 0.69 |
| ▸ | RARA | P10276 | 3/20 | 0.69 |
| ▸ | RXRB | P28702 | 8/20 | 0.46 |
| ▸ | CYP26A1 | O43174 | 5/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | CYP26B1 | Q9NR63 | 5/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7723065 | 0.81 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7723063 | 0.81 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL6917149 | 0.78 | RXRA (0.51) | RXRARXRGRARBRARGRARA | |
| SCHEMBL6908853 | 0.77 | RXRA (0.46) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7732097 | 0.77 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL7732095 | 0.77 | RXRA (1.00) | RXRARXRGRARBRARGRARA | |
| SCHEMBL8015596 | 0.77 | RXRA (0.74) | RXRARXRGRARBRARGRARA | |
| SCHEMBL6915807 | 0.76 | RXRA (0.47) | RXRARXRGRARBRARGRARA | |
| SCHEMBL8015943 | 0.75 | RXRA (0.71) | RXRARXRGRARBRARGRARA | |
| SCHEMBL8419189 | 0.75 | RXRA (0.67) | RXRARXRGRARBRARGRARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000026173-A1 | NOVEL RETINOIDS, METHODS FOR THEIR PRODUCTION AND USE | LIGAND PHARMACEUTICALS INCORPORATED (DE) | 2000-05-11 | — | — | WO | disclosed |
| US-6005007-A | SKIN DISORDERS | LIGAND PHARMACEUTICALS INCORPORATED | 1999-12-21 | — | — | US | disclosed |