SCHEMBL8419189

SCHEMBL8419189

CCC(C(=O)O)=C(C)C=CCC1(c2cc(C(C)(C)C)cc(C(C)(C)C)c2)CC1

nearest known ligand 0.67

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
RXRA P19793 17/20 0.67
RXRG P48443 16/20 0.67
RARA P10276 3/20 0.67
RARB P10826 3/20 0.67
RARG P13631 3/20 0.67
RXRB P28702 11/20 0.37
FFAR4 Q5NUL3 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8015943 0.82 RXRA (0.71) RXRARXRGRARARARBRARG
SCHEMBL7731728 0.80 RXRA (1.00) RXRARXRGRARARARBRARG
SCHEMBL7731726 0.80 RXRA (1.00) RXRARXRGRARARARBRARG
SCHEMBL8012499 0.75 RXRA (0.73) RXRARXRGRARARARBRARG
SCHEMBL8015602 0.75 RXRA (0.69) RXRARXRGRARARARBRARG
SCHEMBL8160450 0.72 RXRA (0.38) RXRARXRGRARARARBRARG
SCHEMBL8145948 0.71 RXRA (0.60) RXRARXRGRARARARBRARG
SCHEMBL8007142 0.71 RXRA (0.56) RXRARXRGRARARARBRARG
SCHEMBL6917149 0.68 RXRA (0.51) RXRARXRGRARARARBRARG
SCHEMBL8154607 0.68 RXRA (0.43) RXRARXRGRARARARBRARG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6005007-A SKIN DISORDERS LIGAND PHARMACEUTICALS INCORPORATED 1999-12-21 US disclosed