Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619140 | 0.83 | CYP2D6 (0.47) | MAPTESR1S1PR1USP2CYP1A2 | |
| SCHEMBL39946 | 0.83 | ESR1 (0.44) | MAPTESR1S1PR1CYP1A2MEN1 | |
| SCHEMBL9818045 | 0.83 | ESR1 (0.44) | MAPTESR1S1PR1CYP1A2MEN1 | |
| Benzene SCHEMBL27985319 | 0.83 | ESR1 (0.44) | MAPTESR1S1PR1CYP1A2MEN1 | |
| Water SCHEMBL10786878 | 0.81 | ESR1 (0.43) | MAPTESR1S1PR1CYP1A2MEN1 | |
| Methane SCHEMBL27634949 | 0.81 | ESR1 (0.43) | MAPTESR1S1PR1CYP1A2MEN1 | |
| Ammonia Solution, Strong SCHEMBL28398668 | 0.81 | ESR1 (0.43) | MAPTESR1S1PR1CYP1A2MEN1 | |
| SCHEMBL8064471 | 0.78 | MAPT (0.45) | MAPTSMN1; SMN2CRHBPCRHR2NPSR1 | |
| SCHEMBL6182129 | 0.77 | MAPT (0.38) | MAPTSMN1; SMN2ALDH1A1LMNA | |
| SCHEMBL13740973 | 0.76 | CYP2D6 (0.52) | MAPTCYP1A2MEN1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0543402-B1 | Aralkylaminopyrimidine derivative, method for preparing the same and composition for controlling noxious organisms | UBE INDUSTRIES (JP) | 2000-03-01 | — | — | EP | disclosed |