Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.40 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.37 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.37 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.37 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.37 |
| ▸ | DRD1 | P21728 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10619140 | 0.91 | CYP2D6 (0.47) | CYP2D6CYP2C19HDAC1HDAC6HDAC3 | |
| SCHEMBL28002283 | 0.88 | CYP2D6 (0.42) | CYP2D6CYP2C19HDAC1HDAC6HDAC3 | |
| SCHEMBL175241 | 0.84 | CHRM2 (0.44) | CYP2D6CYP2C19MAPTNPC1RAB9A | |
| SCHEMBL11299481 | 0.84 | CYP2D6 (0.41) | CYP2D6CYP2C19HDAC1HDAC6HDAC3 | |
| SCHEMBL9278864 | 0.82 | CYP2D6 (0.42) | CYP2D6CYP2C19HDAC1HDAC6HDAC3 | |
| SCHEMBL4070519 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL9302381 | 0.81 | CYP2D6 (0.41) | CYP2D6CYP2C19HDAC1HDAC6HDAC3 | |
| SCHEMBL31497259 | 0.81 | CYP2D6 (0.49) | CYP2D6CYP2C19MAPTKMT2AMEN1 | |
| SCHEMBL9300866 | 0.81 | CYP2D6 (0.41) | CYP2D6CYP2C19HDAC1HDAC6HDAC3 | |
| SCHEMBL6395273 | 0.81 | CYP2D6 (0.41) | CYP2D6CYP2C19HDAC1HDAC6HDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118223047-A | Method for synthesizing N-Mannich alkali compound by taking methanol as carbon source under electric assistance | 天津科技大学 | 2024-06-21 | — | — | CN | disclosed |
| US-9051345-B2 | Metalloinsertor complexes targeted to DNA mismatches | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2015-06-09 | — | — | US | disclosed |
| US-8859533-B2 | Metalloinsertor complexes targeted to DNA mismatches | CALIFORNIA INSTITUTE OF TECHNOLOGY (US) | 2014-10-14 | — | — | US | disclosed |
| EP-2707377-A2 | METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES | California Institute of Technology (US) | 2014-03-19 | — | — | EP | disclosed |
| US-20130345189-A1 | METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2013-12-26 | — | — | US | disclosed |
| CN-101400640-B | Method for producing 1,2-phenylethane compound using atom transfer radical coupling reaction | NIPPON SODA CO | 2013-05-08 | — | — | CN | disclosed |
| US-20130090319-A1 | METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES | CALIFORNIA INSTITUTE OF TECHNOLOGY | 2013-04-11 | — | — | US | disclosed |
| WO-2012155004-A2 | METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES | CALIFORNIA INSITUTE OF TECHNOLOGY (US) | 2012-11-15 | — | — | WO | disclosed |
| CN-101087813-B | Method for removing metal and method for producing polymer | NIPPON SODA CO | 2010-05-12 | — | — | CN | disclosed |
| CN-100594184-C | Dispersion of titanium oxide particles, titanium oxide thin film, solution for forming organic functional film, substrate having organic functional film formed thereon and method for producing same | NIPPON SODA CO | 2010-03-17 | — | — | CN | disclosed |
| CN-100551944-C | Polymer solid electrolyte | NIPPON SODA CO (JP) | 2009-10-21 | — | — | CN | disclosed |
| CN-101115682-A | Dispersion of titanium oxide particles, titanium oxide thin film, solution for forming organic functional film, substrate having organic functional film formed thereon and method for producing same | NIPPON SODA CO (JP) | 2008-01-30 | — | — | CN | disclosed |
| CN-101087813-A | Method for removing metal and method for producing polymer | NIPPON SODA CO (JP) | 2007-12-12 | — | — | CN | disclosed |
| CN-1668662-A | Solid polymer electrolyte | NIPPON SODA CO (JP) | 2005-09-14 | — | — | CN | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20130090319-A1 | METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES | MSH2, MSH6, PMS2 | CYP2D6 2293/4885CYP2C19 3522/4885HDAC1 3701/4885 |
| US-20130345189-A1 | METALLOINSERTOR COMPLEXES TARGETED TO DNA MISMATCHES | MSH2, MSH6, PMS2 | CYP2D6 2293/4885CYP2C19 3522/4885HDAC1 3701/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.