Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 1/20 | 0.60 |
| ▸ | CA2 | P00918 | 1/20 | 0.60 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.53 |
| ▸ | HPGD | P15428 | 2/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 4/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 6/20 | 0.51 |
| ▸ | LMNA | P02545 | 4/20 | 0.51 |
| ▸ | MITF | O75030 | 4/20 | 0.51 |
| ▸ | HTT | P42858 | 4/20 | 0.51 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TP53 | P04637 | 2/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8031666 | 0.91 | NPSR1 (0.61) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL8026255 | 0.91 | NPSR1 (0.61) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL11157463 | 0.84 | CYP19A1 (0.57) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL8016109 | 0.83 | CYP19A1 (0.58) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL21349972 | 0.82 | CYP19A1 (0.58) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL29281346 | 0.82 | CYP19A1 (0.55) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL23171685 | 0.81 | EPHX1 (0.58) | CYP19A1ALDH1A1HPGDNPSR1KMT2A | |
| SCHEMBL8031675 | 0.81 | CA1 (0.42) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL4680992 | 0.81 | CA1 (0.42) | CA1CA2CYP19A1ALDH1A1HPGD | |
| SCHEMBL19020467 | 0.81 | CYP19A1 (0.54) | CA1CA2CYP19A1ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020496-A | 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |