Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 2/20 | 0.56 |
| ▸ | CA1 | P00915 | 1/20 | 0.55 |
| ▸ | CA2 | P00918 | 1/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 7/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | MITF | O75030 | 4/20 | 0.53 |
| ▸ | HTT | P42858 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | NTSR1 | P30989 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19020175 | 0.88 | ALDH1A1 (0.57) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL19020467 | 0.86 | CYP19A1 (0.54) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL21350200 | 0.83 | CYP19A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL19020172 | 0.82 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL21350205 | 0.82 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL21350204 | 0.82 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL21350165 | 0.82 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL19020343 | 0.82 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL21350566 | 0.82 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 | |
| SCHEMBL21350180 | 0.82 | ALDH1A1 (0.51) | CYP19A1ALDH1A1HPGDCA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190276389-A1 | SYNTHESIS OF ARYL CYCLOHEXANE ESTER DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | THE PROCTER & GAMBLE COMPANY | 2019-09-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190276389-A1 | SYNTHESIS OF ARYL CYCLOHEXANE ESTER DERIVATIVES USEFUL AS SENSATES IN CONSUMER PRODUCTS | CUTA, TAS2R8, TRPA1 | CYP19A1 850/4885ALDH1A1 1425/4885HPGD 408/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.