Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 2/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.54 |
| ▸ | HPGD | P15428 | 2/20 | 0.54 |
| ▸ | NPSR1 | Q6W5P4 | 5/20 | 0.52 |
| ▸ | MAPT | P10636 | 3/20 | 0.52 |
| ▸ | TSHR | P16473 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.52 |
| ▸ | LMNA | P02545 | 3/20 | 0.52 |
| ▸ | MITF | O75030 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.50 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.49 |
| ▸ | SERPINE1 | P05121 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4316032 | 0.85 | CYP19A1 (0.78) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL8055167 | 0.85 | CYP19A1 (0.78) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL8055165 | 0.85 | CYP19A1 (0.78) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL11157463 | 0.85 | CYP19A1 (0.57) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL2574092 | 0.85 | ALDH1A1 (0.55) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL12166539 | 0.85 | ALDH1A1 (0.55) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL12166956 | 0.85 | ALDH1A1 (0.55) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL12166714 | 0.85 | ALDH1A1 (0.55) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL21350201 | 0.83 | CYP19A1 (0.61) | CYP19A1ALDH1A1HPGDNPSR1MAPT | |
| SCHEMBL12858216 | 0.83 | CYP19A1 (0.61) | CYP19A1ALDH1A1HPGDNPSR1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6020496-A | 5-alkoxy-2(3H)-oxazolone compounds and process for preparing the same | UBE INDUSTRIES, LTD. (JP) | 2000-02-01 | — | — | US | disclosed |
| EP-0945448-A1 | 5-ALKOXY-2(3H)-OXAZOLONE COMPOUNDS AND PROCESS FOR THE PREPARATION THEREOF | UBE INDUSTRIES, LTD. (JP) | 1999-09-29 | — | — | EP | disclosed |