Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 7/20 | 0.47 |
| ▸ | ALPL | P05186 | 2/20 | 0.44 |
| ▸ | ALPI | P09923 | 2/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 3/20 | 0.39 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017452 | 0.86 | MAPT (0.42) | MAOBALPLALPIMAPTMEN1 | |
| SCHEMBL8032293 | 0.79 | MAOB (0.47) | MAOBACHEMAOAALDH1A1 | |
| SCHEMBL8015825 | 0.76 | KCNH2 (0.43) | MAOBMAPTMEN1KMT2AKCNH2 | |
| SCHEMBL3086161 | 0.72 | MEN1 (0.61) | ALPLALPIMAPTMEN1KMT2A | |
| SCHEMBL7353014 | 0.70 | MAPT (0.52) | MAPTMEN1KMT2AKCNJ1KCNH2 | |
| SCHEMBL8126496 | 0.67 | MEN1 (0.42) | MAOBALPLALPIMAPTMEN1 | |
| SCHEMBL960393 | 0.67 | HSD17B3 (0.70) | MAOBMAPTMEN1KMT2AMAP2K1 | |
| SCHEMBL6635455 | 0.67 | KCNJ1 (0.47) | MAPTMEN1KMT2AKCNJ1KCNH2 | |
| SCHEMBL7449274 | 0.67 | HSD17B3 (0.44) | MAOBALPLALPIACHEMAOA | |
| SCHEMBL7703302 | 0.67 | MEN1 (0.82) | MAPTMEN1KMT2ACYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114532-A | ANTICOAGULANT | BOEHRINGER INGELHEIM PHARMA KG (DE) | 2000-09-05 | — | — | US | disclosed |