SCHEMBL4316032

SCHEMBL4316032

CC1CCC(C(C)C)C(OC(=O)Cc2ccccc2)C1

nearest known ligand 0.78

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.78
ALDH1A1 P00352 6/20 0.58
HPGD P15428 2/20 0.58
NPSR1 Q6W5P4 5/20 0.55
MAPT P10636 4/20 0.55
TSHR P16473 1/20 0.55
MAPK1 P28482 7/20 0.55
LMNA P02545 4/20 0.55
MITF O75030 4/20 0.55
HTT P42858 4/20 0.55
KMT2A Q03164 4/20 0.55
MEN1 O00255 3/20 0.55
SMN1; SMN2 Q16637 3/20 0.55
TP53 P04637 2/20 0.55
NPC1 O15118 1/20 0.55
RAB9A P51151 1/20 0.55
CA1 P00915 1/20 0.51
CA2 P00918 1/20 0.51
KDM4E B2RXH2 1/20 0.51
GAA P10253 1/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8055167 1.00 CYP19A1 (0.78) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL8055165 1.00 CYP19A1 (0.78) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL11932083 0.89 CYP19A1 (0.76) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL21350201 0.88 CYP19A1 (0.61) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL12858216 0.88 CYP19A1 (0.61) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL8016109 0.85 CYP19A1 (0.58) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL23151807 0.84 CYP19A1 (0.57) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL23171767 0.83 CYP19A1 (0.56) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL21349972 0.82 CYP19A1 (0.58) CYP19A1ALDH1A1HPGDNPSR1MAPT
SCHEMBL17363768 0.82 NPSR1 (0.59) CYP19A1ALDH1A1HPGDNPSR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-100522127-C Perfume composition KAO CORP (JP) 2009-08-05 CN claimed
US-11802258-B2 Perfume precursor TAKASAGO INTERNATIONAL CORPORATION (JP) 2023-10-31 US disclosed
US-20210214644-A1 PERFUME PRECURSOR TAKASAGO INTERNATIONAL CORPORATION (JP) 2021-07-15 US disclosed
US-11062794-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2021-07-13 US disclosed
EP-3689849-A1 PERFUME PRECURSOR Takasago International Corporation (JP) 2020-08-05 EP disclosed
US-20180253534-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-09-06 US disclosed
US-10006151-B2 Polyurethane fiber TORAY OPELONTEX CO., LTD. (JP) 2018-06-26 US disclosed
US-9959392-B2 Olfactory signature and odorant mixture having the same YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2018-05-01 US disclosed
EP-2947185-B1 POLYURETHANE FIBER AND ITS USE TORAY OPELONTEX CO LTD (JP) 2018-02-28 EP disclosed
CN-104684412-B Powdery refreshing agent composition 小川香料株式会社 2017-09-01 CN disclosed
CN-104684412-A Powdery refreshing agent composition OGAWA & CO LTD 2015-06-03 CN disclosed
US-20140221269-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2014-08-07 US disclosed
CN-102357061-B Fragrance composition KAO CORP 2013-09-04 CN disclosed
WO-2013035070-A1 OLFACTORY SIGNATURE AND ODORANT MIXTURE HAVING THE SAME YEDA RESEARCH AND DEVELOPMENT CO. LTD. (IL) 2013-03-14 WO disclosed
CN-102357061-A Fragrance composition KAO CORP 2012-02-22 CN disclosed
CN-101579292-A Perfume composition KAO CORP (JP) 2009-11-18 CN disclosed
EP-2020225-A2 Fragrance composition Kao Corporation (JP) 2009-02-04 EP disclosed
US-20050245407-A1 Fragrance composition KAO CORPORATION (JP) 2005-11-03 US disclosed
CN-1674862-A Perfume composition KAO CORP (JP) 2005-09-28 CN disclosed
EP-1552814-A1 FRAGRANCE COMPOSITION Kao Corporation (JP) 2005-07-13 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11802258-B2 Perfume precursor CYP2E1, ADH1A, CYP1A1 CYP19A1 149/4885ALDH1A1 26/4885HPGD 32/4885
US-20210214644-A1 PERFUME PRECURSOR CYP2E1, ADH1A, CYP1A1 CYP19A1 149/4885ALDH1A1 26/4885HPGD 32/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.