Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | Q9HBH1 | 8/20 | 0.74 | |
| ▸ | KDM5A | P29375 | 1/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.58 |
| ▸ | MAPT | P10636 | 5/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.58 |
| ▸ | MEN1 | O00255 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.58 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.58 |
| ▸ | HPGD | P15428 | 3/20 | 0.58 |
| ▸ | USP2 | O75604 | 1/20 | 0.58 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.58 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 4/20 | 0.43 |
| ▸ | HKDC1 | Q2TB90 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | CDC25A | P30304 | 1/20 | 0.43 |
| ▸ | CDC25B | P30305 | 1/20 | 0.43 |
| ▸ | CDC25C | P30307 | 1/20 | 0.43 |
| ▸ | MPI | P34949 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL290186 | 0.85 | PDF (1.00) | PDFKDM5AKMT2AMAPTALDH1A1 | |
| SCHEMBL783241 | 0.85 | PDF (1.00) | PDFKDM5AKMT2AMAPTALDH1A1 | |
| SCHEMBL13077079 | 0.80 | PDF (0.69) | PDFKDM5AKMT2AMAPTALDH1A1 | |
| SCHEMBL801217 | 0.79 | KDM5A (1.00) | PDFKDM5AKMT2AMAPTALDH1A1 | |
| SCHEMBL801284 | 0.75 | PDF (0.66) | PDFMAPT | |
| SCHEMBL973754 | 0.72 | PDF (0.50) | PDFKDM5AMAPTTDP1 | |
| SCHEMBL801226 | 0.70 | NR4A1 (1.00) | PDFKDM5AKMT2AMAPTALDH1A1 | |
| SCHEMBL16994913 | 0.66 | KDM5A (0.78) | PDFKDM5AKMT2AMAPTALDH1A1 | |
| SCHEMBL290235 | 0.65 | PDF (1.00) | PDFKDM5AKMT2AMAPTMEN1 | |
| SCHEMBL13077081 | 0.65 | PDF (0.77) | PDFKDM5AKMT2AMAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120071523-A1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | SLOAN-KETTERING INSTITUTE FOR CANCER RESEARCH (US) | 2012-03-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120071523-A1 | BENZOFURAN-4,5-DIONES AS SELECTIVE PEPTIDE DEFORMYLASE INHIBITORS | PDF, EIF5B, EIF4E | PDF 1/4885KDM5A 245/4885KMT2A 3066/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.