Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | PRKCA | P17252 | 3/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.32 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.32 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21811517 | 0.81 | TSHR (0.40) | TSHRLMNAHCAR2 | |
| SCHEMBL21811640 | 0.77 | LMNA (0.39) | TSHRLMNAHCAR2 | |
| SCHEMBL7067300 | 0.77 | TSHR (0.37) | TSHRLMNAHCAR2 | |
| SCHEMBL7959686 | 0.76 | TSHR (0.36) | TSHRLMNA | |
| SCHEMBL4044174 | 0.75 | TSHR (0.43) | TSHRLMNAPRKCACYP4F2CYP4A11 | |
| SCHEMBL8167504 | 0.75 | — | — | |
| SCHEMBL4246767 | 0.74 | TSHR (0.48) | TSHRLMNAHCAR2 | |
| SCHEMBL21811751 | 0.74 | — | — | |
| SCHEMBL3765857 | 0.73 | TSHR (0.42) | TSHRLMNAPRKCACYP4F2CYP4A11 | |
| SCHEMBL7976432 | 0.73 | TSHR (0.33) | TSHRLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6077952-A | Cephaloporins and homologues | PFIZER INC. (US) | 2000-06-20 | — | — | US | disclosed |
| US-6001997-A | Cephalosporins and homologues, preparations and pharmaceutical compositions | BATESON JOHN HARGREAVES (GB) | 1999-12-14 | — | — | US | disclosed |
| WO-1992001696-A1 | CEPHALOSPORINS AND HOMOLOGUES, PREPARATIONS AND PHARMACEUTICAL COMPOSITIONS | BEECHAM GROUP PLC (GB) | 1992-02-06 | — | — | WO | disclosed |