SCHEMBL8016463

SCHEMBL8016463

CCC1CCCC(CC)C1N=C=O

nearest known ligand 0.38

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8016460 1.00 ALDH1A1 (0.38) ALDH1A1
SCHEMBL11422745 0.88 ALDH1A1 (0.33) ALDH1A1
SCHEMBL11419828 0.83 CA1 (0.41) ALDH1A1
SCHEMBL439828 0.82 EPHX1 (0.33)
SCHEMBL18855928 0.81 ALDH1A1 (0.37) ALDH1A1
SCHEMBL11451590 0.81 ALDH1A1 (0.37) ALDH1A1
SCHEMBL11589620 0.78 APLNR (0.37)
SCHEMBL4040038 0.77 ALDH1A1 (0.41) ALDH1A1
SCHEMBL4043026 0.77 ALDH1A1 (0.41) ALDH1A1
SCHEMBL10822980 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4510097-A Hindered aliphatic monoisocyanates W. R. GRACE & CO. (US) 1985-04-09 US claimed
US-4211847-A CYCLOHEXYL ISOTHIOCYANATE OR HINDERED CYCLOALIPHATIC ISOCYANATE W. R. GRACE & CO. (US) 1980-07-08 US claimed
EP-0800512-B1 ANTIHERPES PEPTIDOMIMETIC COMPOUNDS BOEHRINGER INGELHEIM CA LTD (CA) 2000-01-05 EP disclosed
US-5846941-A Isosteric antiherpes peptide derivatives II BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1998-12-08 US disclosed
EP-0800512-A1 ANTIHERPES PEPTIDOMIMETIC COMPOUNDS BOEHRINGER INGELHEIM (CANADA) LTD. (CA) 1997-10-15 EP disclosed
WO-1996020171-A1 ANTIHERPES PEPTIDOMIMETIC COMPOUNDS BOEHRINGER INGELHEIM (CANADA) LTD./BOEHRINGER INGELHEIM (CANADA) LTÉE (CA) 1996-07-04 WO disclosed
US-4510097-A Hindered aliphatic monoisocyanates W. R. GRACE & CO. (US) 1985-04-09 US disclosed
US-4211847-A CYCLOHEXYL ISOTHIOCYANATE OR HINDERED CYCLOALIPHATIC ISOCYANATE W. R. GRACE & CO. (US) 1980-07-08 US disclosed