Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | PHGDH | O43175 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6830787 | 0.74 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| SCHEMBL96680 | 0.74 | HTT (0.48) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| SCHEMBL465455 | 0.73 | NPSR1 (0.41) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| Hydrochloric Acid SCHEMBL27416015 | 0.72 | HTT (0.46) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| SCHEMBL15052257 | 0.69 | HTT (0.43) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| SCHEMBL8370301 | 0.67 | HTT (0.59) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| SCHEMBL8532403 | 0.64 | ALDH1A1 (0.46) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| SCHEMBL7081836 | 0.63 | ALDH1A1 (0.37) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 | |
| SCHEMBL3082968 | 0.63 | MEN1 (0.42) | ALDH1A1L3MBTL1MAPTTDP1MEN1 | |
| SCHEMBL18889454 | 0.63 | HTT (0.54) | ALDH1A1L3MBTL1MAPTCYP3A4TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109071622-B | Peptides with anticancer activity | IDP研发制药有限公司（ES） | 2023-01-13 | — | — | CN | disclosed |
| CN-114929672-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2022-08-19 | — | — | CN | disclosed |
| CN-114174281-A | Degradation agent for cyclin dependent kinase 7(CDK7) and use thereof | 达纳-法伯癌症研究公司 | 2022-03-11 | — | — | CN | disclosed |
| CN-113956315-A | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2022-01-21 | — | — | CN | disclosed |
| CN-107936076-B | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-10-15 | — | — | CN | disclosed |
| CN-113234114-A | 3, 3-disubstituted 19-norpregnane compounds, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-08-10 | — | — | CN | disclosed |
| CN-108976272-B | 3, 3-disubstituted 19-norpregnane compounds, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2021-05-25 | — | — | CN | disclosed |
| CN-112312899-A | Cancer therapy targeting cancer stem cells | 治疗方案股份有限公司 | 2021-02-02 | — | — | CN | disclosed |
| CN-112057457-A | Neuroactive steroids, compositions, and uses thereof | 萨奇治疗股份有限公司 | 2020-12-11 | — | — | CN | disclosed |
| CN-111433211-A | Synthesis of halichondrin | 哈佛大学的校长及成员们 | 2020-07-17 | — | — | CN | disclosed |
| EP-0573182-B1 | Process for extracting metal values | AVECIA LTD (GB) | 2000-01-05 | — | — | EP | disclosed |
| US-5728853-A | AMIDO(BISTHIOPHOSHORYL) COMPOUNDS USEFUL FOR EXTRACTING METAL VALUES FROM AQUEOUS SOLUTIONS OF METAL SALTS | ZENECA LIMITED (GB) | 1998-03-17 | — | — | US | disclosed |
| US-5557003-A | SOLVENT EXTRACTION OF ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-09-17 | — | — | US | disclosed |
| US-5502250-A | HYDROMETALLURGICAL PROCESS FOR EXTRACTING ZINC FROM ORE | ZENECA LIMITED (GB) | 1996-03-26 | — | — | US | disclosed |
| US-5433855-A | Solvent extraction | ZENECA LIMITED (GB) | 1995-07-18 | — | — | US | disclosed |
| US-5393431-A | Solvent extraction using a aminobis(thiophosphoryl) compound | ZENECA LIMITED (GB) | 1995-02-28 | — | — | US | disclosed |
| EP-0573182-A1 | Process for extracting metal values | ZENECA LIMITED (GB) | 1993-12-08 | — | — | EP | disclosed |