Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.34 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.34 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC7 | Q8WUI4 | 2/20 | 0.34 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.34 |
| ▸ | HDAC10 | Q969S8 | 2/20 | 0.34 |
| ▸ | HDAC11 | Q96DB2 | 2/20 | 0.34 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | HDAC9 | Q9UKV0 | 2/20 | 0.34 |
| ▸ | HDAC5 | Q9UQL6 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.31 |
| ▸ | ORAI2 | Q96SN7 | 1/20 | 0.31 |
| ▸ | ORAI3 | Q9BRQ5 | 1/20 | 0.31 |
| ▸ | TRPV6 | Q9H1D0 | 1/20 | 0.31 |
| ▸ | KCNN4 | O15554 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5712229 | 0.93 | CYP3A4 (0.33) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25406909 | 0.87 | TRPV6 (0.39) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL7661019 | 0.84 | HDAC3 (0.31) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL25409958 | 0.84 | HDAC3 (0.36) | HDAC3HDAC4HDAC1HDAC7HDAC2 | |
| SCHEMBL8023303 | 0.83 | KIF11 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19KIF11 | |
| SCHEMBL8016473 | 0.83 | KIF11 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19KIF11 | |
| SCHEMBL7666679 | 0.83 | KIF11 (0.47) | CYP3A4CYP2D6CYP2C9CYP2C19KIF11 | |
| SCHEMBL5143617 | 0.82 | KCNN4 (0.36) | HDAC6CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL2675133 | 0.81 | KIF11 (0.48) | CYP3A4CYP2D6CYP2C9CYP2C19KIF11 | |
| SCHEMBL8019383 | 0.81 | KIF11 (0.50) | HDAC3HDAC4HDAC1HDAC7HDAC2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6096794-A | PHOTOINITIATOR SYSTEM FOR PHOTOPOLYMERIZATION OF ETHYLENICALLY UNSATURATED POLYMERIZABLE COMPOUNDS | CIBA SPECIALTY CHEMICALS CORPORATION (US) | 2000-08-01 | — | — | US | disclosed |