Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 14/20 | 0.63 |
| ▸ | ACE | P12821 | 11/20 | 0.63 |
| ▸ | CPA1 | P15085 | 2/20 | 0.48 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8016970 | 1.00 | MME (0.63) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL8026904 | 0.94 | MME (0.73) | MMEACECPA1ACE2 | |
| SCHEMBL8026903 | 0.94 | MME (0.73) | MMEACECPA1ACE2 | |
| SCHEMBL8017258 | 0.89 | MME (0.52) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL8017263 | 0.89 | MME (0.52) | MMEACECPA1ACE2L3MBTL1 | |
| SCHEMBL8027283 | 0.87 | MME (0.75) | MMEACECPA1ACE2 | |
| SCHEMBL8016955 | 0.86 | MME (0.64) | MMEACECPA1ACE2 | |
| SCHEMBL8017182 | 0.85 | MME (0.59) | MMEACECPA1ACE2 | |
| SCHEMBL8017176 | 0.85 | MME (0.59) | MMEACECPA1ACE2 | |
| SCHEMBL8028951 | 0.84 | ACE (0.58) | MMEACECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |