Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 12/20 | 0.58 |
| ▸ | MME | P08473 | 11/20 | 0.58 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.46 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.46 |
| ▸ | PPARG | P37231 | 4/20 | 0.45 |
| ▸ | PPARA | Q07869 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | CPA1 | P15085 | 1/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8027402 | 0.91 | ACE (0.48) | ACEMMEOPRM1OPRD1OPRK1 | |
| SCHEMBL8029454 | 0.88 | ACE (0.57) | ACEMMEITGB1ITGA4PPARG | |
| SCHEMBL8026904 | 0.88 | MME (0.73) | ACEMMECPA1ACE2 | |
| SCHEMBL8026903 | 0.88 | MME (0.73) | ACEMMECPA1ACE2 | |
| SCHEMBL8027420 | 0.87 | MME (0.77) | ACEMMEPPARGPPARAMEN1 | |
| SCHEMBL27446259 | 0.86 | OPRM1 (0.45) | ACEMMEOPRM1OPRD1OPRK1 | |
| SCHEMBL8030487 | 0.84 | ACE (0.74) | ACEMMEOPRM1OPRD1OPRK1 | |
| SCHEMBL8027312 | 0.84 | ACE (0.61) | ACEMMEITGB1ITGA4PPARG | |
| SCHEMBL8016970 | 0.84 | MME (0.63) | ACEMMECPA1ACE2 | |
| SCHEMBL8016965 | 0.84 | MME (0.63) | ACEMMECPA1ACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| CN-1138321-A | 1, 3-dialkyl urea derivative with hydrocarbon group | SANTAN PHARMACEUTICAL CO LTD (JP) | 1996-12-18 | — | — | CN | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |