Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 12/20 | 0.59 |
| ▸ | ACE | P12821 | 12/20 | 0.59 |
| ▸ | ACE2 | Q9BYF1 | 9/20 | 0.50 |
| ▸ | CPA1 | P15085 | 8/20 | 0.50 |
| ▸ | ITGB3 | P05106 | 2/20 | 0.46 |
| ▸ | ITGAV | P06756 | 1/20 | 0.46 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.45 |
| ▸ | CTSB | P07858 | 1/20 | 0.44 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8017182 | 1.00 | MME (0.59) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL27464097 | 0.95 | ACE (0.52) | MMEACEACE2CPA1CTSB | |
| SCHEMBL8016973 | 0.92 | MME (0.53) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL8027402 | 0.89 | ACE (0.48) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL8026903 | 0.89 | MME (0.73) | MMEACEACE2CPA1 | |
| SCHEMBL8026904 | 0.89 | MME (0.73) | MMEACEACE2CPA1 | |
| SCHEMBL8030684 | 0.88 | MME (0.62) | MMEACEACE2CPA1CTSB | |
| SCHEMBL8028772 | 0.87 | MME (0.58) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL8028768 | 0.87 | MME (0.58) | MMEACEACE2CPA1ITGB3 | |
| SCHEMBL8017258 | 0.87 | MME (0.52) | MMEACEACE2CPA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |