Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 11/20 | 0.62 |
| ▸ | ACE | P12821 | 11/20 | 0.62 |
| ▸ | CTSL | P07711 | 1/20 | 0.51 |
| ▸ | CTSB | P07858 | 1/20 | 0.51 |
| ▸ | CTSS | P25774 | 1/20 | 0.51 |
| ▸ | CPA1 | P15085 | 2/20 | 0.50 |
| ▸ | ACE2 | Q9BYF1 | 2/20 | 0.50 |
| ▸ | TACR1 | P25103 | 1/20 | 0.49 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27462736 | 0.95 | TACR1 (0.55) | MMEACECTSLCTSBCTSS | |
| SCHEMBL8016973 | 0.93 | MME (0.53) | MMEACECTSLCTSBCTSS | |
| SCHEMBL8027283 | 0.90 | MME (0.75) | MMEACECPA1ACE2CA2 | |
| SCHEMBL8017170 | 0.88 | MME (0.61) | MMEACECTSLCTSBCTSS | |
| SCHEMBL8017182 | 0.88 | MME (0.59) | MMEACECTSBCPA1ACE2 | |
| SCHEMBL8017176 | 0.88 | MME (0.59) | MMEACECTSBCPA1ACE2 | |
| SCHEMBL8029487 | 0.87 | MME (0.81) | MMEACECTSLCTSBCTSS | |
| SCHEMBL8016985 | 0.87 | MME (0.81) | MMEACECTSLCTSBCTSS | |
| SCHEMBL8027177 | 0.87 | MME (0.81) | MMEACECTSLCTSBCTSS | |
| SCHEMBL8026927 | 0.87 | MME (0.81) | MMEACECTSLCTSBCTSS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0738711-B1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO LTD (JP) | 2000-03-08 | — | — | EP | disclosed |
| EP-0738711-A1 | NOVEL 1,3-DIALKYLUREA DERIVATIVE HAVING HYDROXYL GROUP | SANTEN PHARMACEUTICAL CO., LTD. (JP) | 1996-10-23 | — | — | EP | disclosed |