SCHEMBL8017277

SCHEMBL8017277

O=S(=O)(O)Oc1ccc(O)c2c(OS(=O)(=O)O)cccc12

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CHEK1 O14757 2/20 0.49
FABP1 P07148 1/20 0.43
SLC22A6 Q4U2R8 1/20 0.42
GAA P10253 5/20 0.41
MEN1 O00255 3/20 0.41
ESR1 P03372 3/20 0.41
KMT2A Q03164 3/20 0.41
ESR2 Q92731 3/20 0.41
MAPT P10636 4/20 0.40
TDP1 Q9NUW8 2/20 0.39
ALOX15 P16050 2/20 0.39
HSD17B10 Q99714 2/20 0.39
APP P05067 1/20 0.39
THRB P10828 1/20 0.39
HPGD P15428 1/20 0.39
TSHR P16473 1/20 0.39
CASP1 P29466 1/20 0.39
SNCA P37840 1/20 0.39
RECQL P46063 1/20 0.39
AURKA O14965 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11496031 0.82 AURKA (0.60) CHEK1FABP1SLC22A6GAAMEN1
SCHEMBL10647420 0.81 SLC22A6 (0.53) CHEK1FABP1SLC22A6GAAMEN1
SCHEMBL627133 0.80 GAA (0.50) CHEK1SLC22A6GAAMEN1ESR1
SCHEMBL24194428 0.76 MAPT (0.48) CHEK1GAAMEN1ESR1KMT2A
SCHEMBL11498859 0.76 AURKA (0.45) CHEK1FABP1SLC22A6GAAMEN1
SCHEMBL10606230 0.76 FABP1 (0.40) CHEK1FABP1SLC22A6GAAMEN1
SCHEMBL275479 0.74 SLC22A6 (0.51) FABP1SLC22A6GAAMEN1KMT2A
SCHEMBL2522034 0.74 FABP1 (0.48) CHEK1FABP1SLC22A6MEN1KMT2A
SCHEMBL1879537 0.74 LMNA (0.50) FABP1SLC22A6GAAMEN1ESR1
SCHEMBL6747882 0.74 FABP1 (0.63) CHEK1FABP1SLC22A6GAAMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0648816-B1 Dyeing of leather with dyestuff mixtures CIBA SC HOLDING AG (CH) 2000-01-26 EP disclosed
EP-0648816-A1 Dyeing of leather with dyestuff mixtures CIBA-GEIGY AG (CH) 1995-04-19 EP disclosed
EP-0231147-B1 PROCESS FOR THE TRICHROMATIC DYEING OF LEATHER CIBA-GEIGY AG (CH) 1992-01-15 EP disclosed
EP-0181836-B1 PROCESS FOR IMPROVING THE LIGHT FASTNESS OF DYED LEATHERS CIBA-GEIGY AG (CH) 1988-12-21 EP disclosed
EP-0231147-A2 Process for the trichromatic dyeing of leather CIBA-GEIGY AG (CH) 1987-08-05 EP disclosed
EP-0181836-A1 Process for improving the light fastness of dyed leathers CIBA-GEIGY AG (CH) 1986-05-21 EP disclosed
EP-0061670-B1 PROCESS FOR DYEING LEATHER AND PELTS WITH DYE MIXTURES CIBA-GEIGY AG (CH) 1985-06-12 EP disclosed
EP-0061670-A1 Process for dyeing leather and pelts with dye mixtures CIBA-GEIGY AG (CH) 1982-10-06 EP disclosed