SCHEMBL627133

SCHEMBL627133

O=S(=O)(O)Oc1ccc(O)c2ccccc12

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 5/20 0.50
MEN1 O00255 5/20 0.50
KMT2A Q03164 5/20 0.50
IDO1 P14902 4/20 0.50
ESR1 P03372 4/20 0.50
ESR2 Q92731 4/20 0.50
SLC22A6 Q4U2R8 1/20 0.50
LDHA P00338 1/20 0.48
CHEK1 O14757 1/20 0.46
EP300 Q09472 2/20 0.43
KAT2B Q92831 2/20 0.43
KAT8 Q9H7Z6 2/20 0.43
MAPT P10636 3/20 0.41
ALOX15 P16050 3/20 0.41
SMN1; SMN2 Q16637 3/20 0.41
HSD17B10 Q99714 3/20 0.41
JAK2 O60674 1/20 0.41
USP2 O75604 1/20 0.41
NPSR1 Q6W5P4 1/20 0.41
HDAC3 O15379 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7159703 0.83 GAA (0.50) GAAMEN1KMT2AIDO1ESR1
SCHEMBL10647420 0.81 SLC22A6 (0.53) GAAMEN1KMT2AESR1ESR2
SCHEMBL8017277 0.80 CHEK1 (0.49) GAAMEN1KMT2AESR1ESR2
SCHEMBL24614327 0.79 SLC22A6 (0.49) GAAMEN1KMT2AESR1ESR2
SCHEMBL11124814 0.79 IDO1 (0.53) GAAMEN1KMT2AIDO1ESR1
SCHEMBL29414155 0.79 IDO1 (0.53) GAAMEN1KMT2AIDO1ESR1
SCHEMBL6216338 0.76 COMT (0.60) GAAMEN1KMT2AIDO1MAPT
SCHEMBL5329107 0.76 MAPT (0.46) MEN1KMT2ASLC22A6CHEK1MAPT
SCHEMBL235067 0.75 HSD11B1 (0.50) GAAMEN1KMT2AESR1ESR2
SCHEMBL29382842 0.75 HSD11B1 (0.50) GAAMEN1KMT2AESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9622959-B2 Cross-linked polymere CLARIANT INTERNATIONAL LTD. (CH) 2017-04-18 US disclosed
EP-2739261-A1 COSMETIC, DERMATOLOGICAL OR PHARMACEUTICAL COMPOSITIONS COMPRISING ISOSORBIDE DIESTERS AND UV FILTERS Clariant International Ltd. (CH) 2014-06-11 EP disclosed
EP-2739148-A1 COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALIPHATIC VICINAL DIOLS Clariant International Ltd. (CH) 2014-06-11 EP disclosed
EP-2739151-A1 COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE SUBSTANCES Clariant International Ltd. (CH) 2014-06-11 EP disclosed
EP-2739152-A1 COMPOSITIONS CONTAINING ISOSORBIDE MONOESTER AND ALCOHOLS THAT CONTAIN AT LEAST ONE AROMATIC GROUP Clariant International Ltd. (CH) 2014-06-11 EP disclosed
EP-2739149-A1 COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND ISOTHIAZOLINONES Clariant International Ltd. (CH) 2014-06-11 EP disclosed
US-20140127147-A1 Cross-linked Polymere CLARIANT FINANCE (BVI) LIMITED (VG) 2014-05-08 US disclosed
EP-2683752-A1 CROSS-LINKED POLYMERS Clariant Finance (BVI) Limited (VG) 2014-01-15 EP disclosed
EP-2683751-A1 POLYMERS BASED ON SULFONIC ACIDS, AMIDES AND SPECIAL CROSS-LINKING AGENTS Clariant International Ltd. (CH) 2014-01-15 EP disclosed
EP-2651816-A1 COMPOSITIONS CONTAINING HYDROGEN PEROXIDE OR SUBSTANCES RELEASING HYDROGEN PEROXIDE Clariant Finance (BVI) Limited (VG) 2013-10-23 EP disclosed
WO-2013017262-A1 COMPOSITIONS COMPRISING ISOSORBIDE MONOESTERS AND HALOGENATED ANTIMICROBIAL ACTIVE SUBSTANCES CLARIANT INTERNATIONAL LTD (CH) 2013-02-07 WO disclosed
WO-2012119747-A1 CROSS-LINKED POLYMERS CLARIANT INTERNATIONAL LTD (CH) 2012-09-13 WO disclosed
WO-2012119746-A1 POLYMERS BASED ON SULFONIC ACIDS, AMIDES AND SPECIAL CROSS-LINKING AGENTS CLARIANT INTERNATIONAL LTD (CH) 2012-09-13 WO disclosed
WO-2012079739-A1 COMPOSITIONS CONTAINING HYDROGEN PEROXIDE OR SUBSTANCES RELEASING HYDROGEN PEROXIDE CLARIANT INTERNATIONAL LTD (CH) 2012-06-21 WO disclosed
WO-2012019688-A2 COMPOSITIONS COMPRISING HYDROGEN PEROXIDE OR HYDROGEN PEROXIDE DONOR SUBSTANCES CLARIANT INTERNATIONAL LTD (CH) 2012-02-16 WO disclosed
WO-2011137992-A1 COMPOSITIONS CONTAINING PHOSPHORIC ACID ALKYL ESTERS AND POLYOL ESTERS CLARIANT INTERNATIONAL LTD (CH) 2011-11-10 WO disclosed
WO-2008047210-A2 COMPOUNDS DERIVED FROM 1 -ETHYL-4,5-DIAMINO-PYRAZOLE AND THEIR USE FOR OXIDATIVE DYEING OF KERATIN FIBRES KEMON S.P.A. (IT) 2008-04-24 WO disclosed
EP-1789141-B1 COMPOSITION CONTAINING A DIHYDROXYACETONE PRECURSOR MERCK PATENT GMBH (DE) 2008-03-12 EP disclosed
EP-0013922-A2 Process for dyeing and printing fibrous materials containing hydroxy groups CASSELLA Aktiengesellschaft (DE) 1980-08-06 EP disclosed
EP-0013919-A2 Aqueous dyestuff preparation, process for its production and its use in dyeing and printing CASSELLA Aktiengesellschaft (DE) 1980-08-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140127147-A1 Cross-linked Polymere PCNA, SMC2, SMC1A GAA 3111/4885MEN1 2949/4885KMT2A 1046/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.