Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 2/20 | 0.51 |
| ▸ | DRD2 | P14416 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | AXL | P30530 | 1/20 | 0.49 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.49 |
| ▸ | HTR2A | P28223 | 2/20 | 0.45 |
| ▸ | HTR2B | P41595 | 1/20 | 0.45 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.43 |
| ▸ | TBK1 | Q9UHD2 | 1/20 | 0.43 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.42 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.42 |
| ▸ | DYRK1A | Q13627 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 2/20 | 0.42 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.42 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.42 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1848853 | 0.90 | HTR2C (0.61) | HTR2CDRD2KDM4EALDH1A1MAPT | |
| SCHEMBL10124857 | 0.79 | CDK9 (0.49) | HTR2CDRD2KDM4EALDH1A1MAPT | |
| SCHEMBL12874727 | 0.74 | HTR2C (0.51) | HTR2CDRD2KDM4EALDH1A1MAPT | |
| SCHEMBL3930943 | 0.73 | DYRK1A (0.42) | HTR2CAXLNUDT1HTR2AHTR2B | |
| SCHEMBL12874723 | 0.73 | HTR2C (0.46) | HTR2CDRD2KDM4EALDH1A1MAPT | |
| SCHEMBL24440670 | 0.72 | HTR2A (0.57) | HTR2CAXLHTR2AHTR2BIKBKE | |
| Piperazine SCHEMBL27563143 | 0.72 | NUDT1 (0.81) | HTR2CAXLNUDT1HTR2ASLC6A4 | |
| SCHEMBL38661232 | 0.72 | HTR2C (0.49) | HTR2CDRD2KDM4EALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL27893779 | 0.71 | AXL (0.95) | KDM4EALDH1A1MAPTALOX15AXL | |
| Hydrochloric Acid SCHEMBL5325493 | 0.71 | AXL (0.95) | KDM4EALDH1A1MAPTALOX15AXL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000040581-A1 | 3,4-DIHYDRO-2H-BENZO[1,4]OXAZINE DERIVATIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 2000-07-13 | — | — | WO | disclosed |