Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TAS2R8 | Q9NYW2 | 8/20 | 0.42 |
| ▸ | IGF1R | P08069 | 3/20 | 0.41 |
| ▸ | EGFR | P00533 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.40 |
| ▸ | PPARD | Q03181 | 1/20 | 0.40 |
| ▸ | PPARA | Q07869 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12438863 | 0.92 | IGF1R (0.42) | TAS2R8IGF1RARHSD17B10MEN1 | |
| SCHEMBL12438861 | 0.87 | AR (0.49) | TAS2R8IGF1RAR | |
| SCHEMBL8007160 | 0.85 | AR (0.52) | IGF1RAR | |
| SCHEMBL12438856 | 0.81 | AR (0.65) | TAS2R8IGF1RAR | |
| SCHEMBL8026324 | 0.78 | AR (0.43) | TAS2R8IGF1RPPARGPPARDPPARA | |
| SCHEMBL2216371 | 0.78 | PGR (0.56) | AR | |
| SCHEMBL12873227 | 0.76 | TAS2R8 (0.43) | TAS2R8PPARGPPARDPPARAAR | |
| SCHEMBL8019167 | 0.72 | CYP3A4 (0.49) | TAS2R8AR | |
| SCHEMBL8019174 | 0.70 | AR (0.44) | TAS2R8IGF1RAR | |
| SCHEMBL12603149 | 0.68 | AR (0.45) | TAS2R8IGF1RPPARGPPARDPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009097995-A1 | NOVEL PHENYL-SUBSTITUTED IMIDAZOLIDINES, METHOD FOR THE PRODUCTION THEREOF, MEDICAMENTS CONTAINING SAID COMPOUNDS AND USE THEREOF | SANOFI-AVENTIS (FR) | 2009-08-13 | — | — | WO | disclosed |