SCHEMBL8017389

SCHEMBL8017389

C=CNC(=O)CCC(=O)NCCO

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 5/20 0.43
ALDH1A1 P00352 4/20 0.43
GAA P10253 1/20 0.42
MEN1 O00255 2/20 0.40
BLM P54132 2/20 0.40
KMT2A Q03164 2/20 0.40
TRPV1 Q8NER1 2/20 0.40
TRPM8 Q7Z2W7 1/20 0.40
FAAH O00519 1/20 0.40
KCNK3 O14649 1/20 0.40
CNR2 P34972 1/20 0.40
HPGD P15428 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
ALOX12 P18054 1/20 0.39
TDP1 Q9NUW8 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2186533 0.82 GAA (0.53) CNR1ALDH1A1GAAMEN1BLM
SCHEMBL8440530 0.80
SCHEMBL4579858 0.78
SCHEMBL13528442 0.77 CNR1 (0.53) CNR1ALDH1A1MEN1BLMKMT2A
SCHEMBL7628967 0.76
SCHEMBL622441 0.74
SCHEMBL223005 0.73 PHF8 (0.50) ALDH1A1MEN1BLMKMT2ALMNA
SCHEMBL1416230 0.73
SCHEMBL7144946 0.73 GAA (0.47) CNR1ALDH1A1GAAMEN1BLM
SCHEMBL2484600 0.73 PHF8 (0.50) CNR1ALDH1A1GAAKMT2ACNR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762197-B1 Photographic recording material AGFA GEVAERT AG (DE) 2000-01-12 EP disclosed
US-5888719-A CONTINING A POLYMER; DARK DECAY STABILITY AGFA-GEVAERT AG (DE) 1999-03-30 US disclosed
US-5674668-A Photographic recording material AGFA-GEVAERT (DE) 1997-10-07 US disclosed
EP-0762197-A1 Photographic recording material Agfa-Gevaert AG (DE) 1997-03-12 EP disclosed
US-5518877-A POLYPEPTIDE-ADDITION POLYMER AGFA-GEVAERT AG (DE) 1996-05-21 US disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed
US-4865946-A CROSSLINKED KETO-SUBSTITUTED ACRYLAMIDE COPOLYMER EASTMAN KODAK COMPANY (US) 1989-09-12 US disclosed
EP-0042307-B1 AN OPTICAL RECORDING ELEMENT AND A METHOD OF RECORDING INFORMATION USING THE ELEMENT EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1986-09-10 EP disclosed
EP-0137672-A2 Photographic material with a barrier layer comprising a chill-gelable polymer and a method for coating it EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1985-04-17 EP disclosed
US-4504569-A OF AN ACRYLAMIDE EASTMAN KODAK COMPANY (US) 1985-03-12 US disclosed
EP-0121141-A2 Chill-gelable polymers and their use EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1984-10-10 EP disclosed
US-4340655-A Thermal and mechanical barrier layers for optical recording elements EASTMAN KODAK COMPANY (US) 1982-07-20 US disclosed
EP-0042307-A2 An optical recording element and a method of recording information using the element EASTMAN KODAK COMPANY (a New Jersey corporation) (US) 1981-12-23 EP disclosed