Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.43 |
| ▸ | FAAH | O00519 | 1/20 | 0.38 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 2/20 | 0.33 |
| ▸ | DRD3 | P35462 | 2/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8096069 | 1.00 | MAOB (0.43) | MAOBFAAHMAOAL3MBTL1SLC6A3 | |
| SCHEMBL8018504 | 0.92 | MAOB (0.40) | MAOBFAAHMAOAL3MBTL1SLC6A3 | |
| SCHEMBL8018501 | 0.92 | MAOB (0.40) | MAOBFAAHMAOAL3MBTL1SLC6A3 | |
| SCHEMBL8018499 | 0.92 | MAOB (0.40) | MAOBFAAHMAOAL3MBTL1SLC6A3 | |
| SCHEMBL8098806 | 0.86 | HRH3 (0.43) | SLC6A3 | |
| SCHEMBL8098809 | 0.86 | HRH3 (0.43) | SLC6A3 | |
| SCHEMBL8092154 | 0.86 | MAOB (0.43) | MAOBMAOAGPR84 | |
| SCHEMBL8092153 | 0.86 | MAOB (0.43) | MAOBMAOAGPR84 | |
| SCHEMBL7771511 | 0.86 | CHKA (0.34) | MAOBFAAHSLC6A3DRD2DRD3 | |
| SCHEMBL7771512 | 0.86 | CHKA (0.34) | MAOBFAAHSLC6A3DRD2DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0668286-B1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | SHINETSU CHEMICAL CO (JP) | 2000-12-20 | — | — | EP | disclosed |
| US-5523440-A | Silacyclohexane compound, a method of preparaing it and a liquid crystal composition containing it | SHIN-ETSU CHEMICAL CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0668286-A1 | A silacyclohexane compound, a method of preparing it and a liquid crystal composition containing it | Shin-Etsu Chemical Co., Ltd. (JP) | 1995-08-23 | — | — | EP | disclosed |