Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GART | P22102 | 11/20 | 0.54 |
| ▸ | DHFR | P00374 | 3/20 | 0.43 |
| ▸ | FOLR1 | P15328 | 2/20 | 0.41 |
| ▸ | ATIC | P31939 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7499714 | 1.00 | GART (0.54) | GARTDHFRFOLR1ATIC | |
| SCHEMBL8017846 | 0.87 | GART (0.40) | GARTDHFRFOLR1 | |
| SCHEMBL8017849 | 0.87 | GART (0.40) | GARTDHFRFOLR1 | |
| SCHEMBL8819976 | 0.86 | GART (0.59) | GARTDHFRATIC | |
| SCHEMBL7491867 | 0.86 | GART (0.57) | GARTDHFRATIC | |
| SCHEMBL7495598 | 0.86 | GART (0.53) | GARTDHFRFOLR1ATIC | |
| SCHEMBL7497232 | 0.86 | GART (0.52) | GARTDHFRFOLR1ATIC | |
| SCHEMBL7553633 | 0.85 | GART (0.58) | GARTDHFRATIC | |
| SCHEMBL7494031 | 0.85 | GART (0.54) | GARTDHFRATIC | |
| SCHEMBL7496781 | 0.85 | GART (0.58) | GARTDHFRATIC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6066639-A | ANTITUMOR AGENTS | THE TRUSTEES OF PRINCETON UNIVERSITY (US) | 2000-05-23 | — | — | US | disclosed |