Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FBP1 | P09467 | 1/20 | 0.45 |
| ▸ | IGF2R | P11717 | 4/20 | 0.43 |
| ▸ | AMDHD2 | Q9Y303 | 1/20 | 0.37 |
| ▸ | TLR4 | O00206 | 1/20 | 0.37 |
| ▸ | LY96 | Q9Y6Y9 | 1/20 | 0.37 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL898764 | 0.83 | FBP1 (0.46) | FBP1IGF2RAMDHD2 | |
| SCHEMBL898646 | 0.83 | FBP1 (0.46) | FBP1IGF2RAMDHD2 | |
| SCHEMBL15728259 | 0.82 | FBP1 (0.64) | FBP1IGF2RAMDHD2SMPD1 | |
| SCHEMBL15764610 | 0.79 | FBP1 (0.45) | FBP1IGF2R | |
| SCHEMBL897629 | 0.79 | FBP1 (0.45) | FBP1IGF2R | |
| SCHEMBL15631721 | 0.79 | FBP1 (0.45) | FBP1IGF2R | |
| SCHEMBL897632 | 0.79 | FBP1 (0.45) | FBP1IGF2R | |
| SCHEMBL15631722 | 0.73 | FBP1 (0.40) | FBP1IGF2RAMDHD2TLR4 | |
| SCHEMBL11267952 | 0.73 | IGF2R (0.50) | FBP1IGF2RTLR4LY96SMPD1 | |
| SCHEMBL15631733 | 0.73 | FBP1 (0.40) | FBP1IGF2RAMDHD2TLR4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1023301-A1 | A HETEROCYCLIC CHEMICAL COMPOUND | PERSTORP AB (SE) | 2000-08-02 | — | — | EP | disclosed |
| US-6046334-A | Heterocyclic chemical compound | PERSTORP AB (SE) | 2000-04-04 | — | — | US | disclosed |
| WO-1997018220-A1 | A HETEROCYCLIC CHEMICAL COMPOUND | PERSTORP AB (SE) | 1997-05-22 | — | — | WO | disclosed |