SCHEMBL898646

SCHEMBL898646

CO[C@H]1O[C@H](COP(=O)(O)O)[C@@H](OP(=O)(O)O)[C@H](OP(=O)(O)O)[C@@H]1OP(=O)(O)O

nearest known ligand 0.67

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
▸ FBP1 P09467 1/20 0.46
▸ IGF2R P11717 4/20 0.40
▸ AMDHD2 Q9Y303 1/20 0.38
▸ ITPR3 Q14573 2/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL898764 1.00 FBP1 (0.46) FBP1IGF2RAMDHD2ITPR3
SCHEMBL15631733 0.89 FBP1 (0.40) FBP1IGF2RAMDHD2
SCHEMBL15631722 0.89 FBP1 (0.40) FBP1IGF2RAMDHD2
SCHEMBL897909 0.87 TLR4 (0.44) ITPR3
SCHEMBL898729 0.87 TLR4 (0.44) ITPR3
SCHEMBL6829446 0.87 TLR4 (0.44) ITPR3
SCHEMBL15631721 0.83 FBP1 (0.45) FBP1IGF2R
SCHEMBL8018689 0.83 FBP1 (0.45) FBP1IGF2RAMDHD2
SCHEMBL15764610 0.83 FBP1 (0.45) FBP1IGF2R
SCHEMBL897632 0.83 FBP1 (0.45) FBP1IGF2R

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140155334-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITÉ DE STRASBOURG (FR) 2014-06-05 — — US claimed
US-20140088036-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITE DE STRASBOURG (FR) 2014-03-27 — — US claimed
US-20210361680-A1 INOSITOL-BASED IMMUNOTHERAPIES NORMOXYS INC (US) 2021-11-25 — — US disclosed
US-20160067267-A1 MYO-INOSITOL TRISPYROPHOSPHATE AS AN ANTI-OBESITY AGENT NORMOXYS, INC. (US) 2016-03-10 — — US disclosed
WO-2015138916-A1 MYO-INOSITOL TRISPYROPHOSHATE AS AN ANTI-DIABETIC AGENT NICOLAU YVES CLAUDE (US) 2015-09-17 — — WO disclosed
US-20140155334-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITÉ DE STRASBOURG (FR) 2014-06-05 — — US disclosed
US-20140088036-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES UNIVERSITE DE STRASBOURG (FR) 2014-03-27 — — US disclosed
EP-2621273-A2 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES Normoxys, Inc. (US) 2013-08-07 — — EP disclosed
WO-2012045009-A2 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES NORMOXYS, INC. (US) 2012-04-05 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140155334-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES PPIP5K2, INPP5A, INPP5B FBP1 60/4885IGF2R 374/4885AMDHD2 486/4885
US-20140088036-A1 POLYPHOSPHATE AND PYROPHOSPHATE DERIVATIVE OF SACCHARIDES PPIP5K2, INPP5A, INPP5B FBP1 60/4885IGF2R 374/4885AMDHD2 486/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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