Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ERCC5 | P28715 | 1/20 | 0.41 |
| ▸ | FEN1 | P39748 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.41 |
| ▸ | CHRNA1 | P02708 | 1/20 | 0.41 |
| ▸ | CHRNG | P07510 | 1/20 | 0.41 |
| ▸ | ITGA5 | P08648 | 1/20 | 0.41 |
| ▸ | CHRNB1 | P11230 | 1/20 | 0.41 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.41 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.41 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8008318 | 0.76 | GRM2 (0.52) | NPSR1MEN1KMT2AERCC5FEN1 | |
| SCHEMBL8020166 | 0.71 | MAPK1 (0.52) | NPSR1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL22209908 | 0.69 | NPSR1 (0.52) | NPSR1MEN1KMT2AALDH1A1SMN1; SMN2 | |
| SCHEMBL17398601 | 0.68 | NPSR1 (0.66) | NPSR1MEN1KMT2AALDH1A1PARP1 | |
| SCHEMBL23931574 | 0.67 | PARP1 (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL17187940 | 0.67 | PARP1 (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL54859 | 0.67 | PARP1 (0.63) | MEN1KMT2AALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL5082350 | 0.66 | NPC1 (0.54) | ALDH1A1SMN1; SMN2MAPTERCC5FEN1 | |
| SCHEMBL10599818 | 0.66 | ERCC5 (0.57) | MEN1KMT2AALDH1A1SMN1; SMN2MAPT | |
| SCHEMBL2165684 | 0.66 | NPSR1 (0.59) | NPSR1MEN1KMT2AALDH1A1PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973720-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.p.A. (IT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998040344-A1 | 2-SUBSTITUTED BENZOYL-CYCLOALKYL-1-CARBOXYLIC ACID DERIVATIVES | PHARMACIA & UPJOHN S.P.A. (IT) | 1998-09-17 | — | — | WO | disclosed |