Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.47 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.42 |
| ▸ | ACACB | O00763 | 1/20 | 0.39 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.36 |
| ▸ | AKR1C2 | P52895 | 3/20 | 0.36 |
| ▸ | NOS3 | P29474 | 2/20 | 0.35 |
| ▸ | NOS1 | P29475 | 2/20 | 0.35 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | PLK1 | P53350 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2195029 | 0.79 | ALOX5 (0.43) | ALOX5SLC6A4ACACBAKR1C3AKR1C2 | |
| SCHEMBL3991740 | 0.76 | TSHR (0.60) | TSHRALOX5ESR1ESR2ALDH1A1 | |
| SCHEMBL8019231 | 0.76 | TSHR (0.60) | TSHRALOX5ESR1ESR2ALDH1A1 | |
| SCHEMBL1200882 | 0.76 | TSHR (0.60) | TSHRALOX5ESR1ESR2ALDH1A1 | |
| SCHEMBL15775527 | 0.75 | SLC6A4 (0.57) | ALOX5SLC6A4ACACBNOS3NOS1 | |
| SCHEMBL6182478 | 0.75 | SLC6A4 (0.50) | ALOX5SLC6A4ACACBAKR1C3AKR1C2 | |
| SCHEMBL13557508 | 0.75 | SLC6A4 (0.50) | ALOX5SLC6A4ACACBAKR1C3AKR1C2 | |
| SCHEMBL11811969 | 0.75 | ACACB (0.43) | ALOX5SLC6A4ACACBAKR1C3AKR1C2 | |
| Hydrochloric Acid SCHEMBL15775544 | 0.73 | SLC6A4 (0.55) | ALOX5SLC6A4ACACBNOS3NOS1 | |
| SCHEMBL2197891 | 0.73 | ALOX5 (0.46) | ALOX5SLC6A4ACACBAKR1C3AKR1C2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0610048-B1 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-09-22 | — | — | EP | claimed |
| US-5580765-A | A CULTURE PRODUCT OF A-HYDROXYNITRILE OR A MIXTURE OF ALDEHYDE AND PRUSSIC ACID | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-12-03 | — | — | US | claimed |
| EP-0610048-A2 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | claimed |
| EP-0711836-B1 | Method of producing optically active alpha-hydroxy acid or alpha-hydroxyamide | MITSUBISHI RAYON CO (JP) | 2000-02-02 | — | — | EP | disclosed |
| EP-0610048-B1 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | MITSUBISHI RAYON CO (JP) | 1999-09-22 | — | — | EP | disclosed |
| US-5736385-A | NITRILASE OR NITRILE HYDRATASE HYDROLYSIS OF A CYANOHYDRIN WHILE AUTOMATICALLY CONTROLLING CYANOHYDRIN CONCENTRATION | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1998-04-07 | — | — | US | disclosed |
| US-5580765-A | A CULTURE PRODUCT OF A-HYDROXYNITRILE OR A MIXTURE OF ALDEHYDE AND PRUSSIC ACID | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-12-03 | — | — | US | disclosed |
| EP-0711836-A1 | Method of producing optically active alpha-hydroxy acid or alpha-hydroxyamide | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1996-05-15 | — | — | EP | disclosed |
| EP-0610048-A2 | Process for producing optically active alpha-hydrocarboxylic acid having phenyl group | NITTO CHEMICAL INDUSTRY CO., LTD. (JP) | 1994-08-10 | — | — | EP | disclosed |