SCHEMBL8019160

SCHEMBL8019160

C=C(CC)C(=O)NCC(=O)O

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGLN1 Q9GZT9 2/20 0.50
PLA2G2A P14555 1/20 0.46
FFAR3 O14843 1/20 0.39
ALDH1A1 P00352 4/20 0.39
MAPT P10636 3/20 0.39
TDP1 Q9NUW8 2/20 0.39
LMNA P02545 2/20 0.39
PTGS2 P35354 1/20 0.39
MME P08473 3/20 0.37
ACE P12821 1/20 0.37
CPA1 P15085 1/20 0.37
ACE2 Q9BYF1 1/20 0.37
CTH P32929 1/20 0.37
APEX1 P27695 2/20 0.35
ECE1 P42892 1/20 0.34
FAAH O00519 5/20 0.34
MEN1 O00255 2/20 0.33
RECQL P46063 2/20 0.33
KMT2A Q03164 2/20 0.33
KDM4E B2RXH2 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8855259 0.86
SCHEMBL10910411 0.78 TDP1 (0.35) FFAR3ALDH1A1TDP1MEN1KMT2A
SCHEMBL29573839 0.78 MEN1 (0.39) PLA2G2AFFAR3ALDH1A1TDP1MEN1
SCHEMBL7936208 0.78
SCHEMBL11349746 0.77 EGLN1 (0.45) EGLN1PLA2G2AALDH1A1MAPTTDP1
SCHEMBL29199471 0.77 EGLN1 (0.55) EGLN1PLA2G2AALDH1A1MAPTTDP1
SCHEMBL12256836 0.77 PLA2G2A (0.69) PLA2G2AALDH1A1TDP1FAAHMEN1
SCHEMBL23295076 0.76 PLA2G2A (0.59) EGLN1PLA2G2AFFAR3ALDH1A1MAPT
SCHEMBL65636 0.76 EGLN1 (0.54) EGLN1PLA2G2AALDH1A1MAPTTDP1
Ammonia Solution, Strong SCHEMBL5428819 0.76 MMP1 (0.36) FFAR3ALDH1A1TDP1FAAHMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0762197-B1 Photographic recording material AGFA GEVAERT AG (DE) 2000-01-12 EP disclosed
EP-0539729-B1 Development inhibitor reflector layers EASTMAN KODAK CO (US) 1998-07-15 EP disclosed
EP-0762197-A1 Photographic recording material Agfa-Gevaert AG (DE) 1997-03-12 EP disclosed
US-5512414-A ELEMENT CONTAINING MORDANT LAYER FOR BINDING DIFFUSIBLE DYES, LAYER CONTAINING SOLID PARTICLE DISPERSION OF DIFFUSIBLE DYE FORMING COMPOUND, BARRIER LAYER WHICH BLOCKS DIFFUSION OF DYE OUT OF ELEMENT EASTMAN KODAK COMPANY (US) 1996-04-30 US disclosed
US-5441854-A Photographic image forming process utilizing a barrier layer for diffusible dye containment EASTMAN KODAK COMPANY (US) 1995-08-15 US disclosed
EP-0666498-A2 Silver halide photographic material Agfa-Gevaert AG (DE) 1995-08-09 EP disclosed
US-5370967-A Polymeric barrier to control diffusion EASTMAN KODAK COMPANY (US) 1994-12-06 US disclosed
US-5342730-A With mordant and stripping layers EASTMAN KODAK COMPANY (US) 1994-08-30 US disclosed
US-5322758-A Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-06-21 US disclosed
EP-0590567-A1 Integral color diffusion transfer element for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590566-A1 Barrier layer for dye containment in photographic elements EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
EP-0590565-A1 Image separation system for large volume development EASTMAN KODAK COMPANY (US) 1994-04-06 EP disclosed
US-5288745-A Diffusion transfer for color photography; polymeric mordant dye barrier layers EASTMAN KODAK COMPANY (US) 1994-02-22 US disclosed
US-5254441-A Barrier polymer layer of hydrophobic and ionic hydrophilic unsaturated monomers EASTMAN KODAK COMPANY (US) 1993-10-19 US disclosed
EP-0539729-A1 Development inhibitor reflector layers EASTMAN KODAK COMPANY (US) 1993-05-05 EP disclosed