Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.33 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.31 |
| ▸ | GPR17 | Q13304 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8005995 | 0.89 | GAA (0.35) | POLBMAPTKDM4EGRIK2RECQL | |
| SCHEMBL8703408 | 0.84 | MMP2 (0.34) | POLBMAPTKDM4EP2RX7NR2F2 | |
| SCHEMBL1225501 | 0.83 | KDM4E (0.40) | POLBMAPTKDM4EP2RX7MEN1 | |
| SCHEMBL12885645 | 0.83 | KDM4E (0.40) | POLBMAPTKDM4EP2RX7MEN1 | |
| SCHEMBL8017376 | 0.83 | KDM4E (0.39) | POLBMAPTKDM4EGRIK2P2RX7 | |
| SCHEMBL8022788 | 0.80 | GAA (0.43) | MEN1KMT2AALDH1A1LMNAGAA | |
| SCHEMBL8019369 | 0.79 | POLB (0.36) | POLBMAPTKDM4EGRIK2ALDH1A1 | |
| SCHEMBL8021762 | 0.79 | CA1 (0.42) | POLBMAPTKDM4EGRIK2P2RX7 | |
| SCHEMBL8019429 | 0.79 | KDM4E (0.36) | POLBMAPTKDM4EGRIK2ALDH1A1 | |
| SCHEMBL8005992 | 0.77 | KDM4E (0.35) | POLBMAPTKDM4EGRIK2P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773920-B1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| US-5808135-A | HERBICIDE; PESTICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0773920-A1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003366-A1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |