Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.30 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8019384 | 0.89 | POLB (0.36) | GAAP2RX7KDM4EPOLBMAPT | |
| SCHEMBL8709109 | 0.85 | KDM4E (0.36) | GAAP2RX7KDM4EPOLBMAPT | |
| SCHEMBL8017376 | 0.84 | KDM4E (0.39) | GAAP2RX7KDM4EPOLBMAPT | |
| SCHEMBL8022788 | 0.81 | GAA (0.43) | GAAALDH1A1EPHX2 | |
| Bicarbonate SCHEMBL8019387 | 0.81 | P2RX7 (0.36) | P2RX7KDM4EPOLBMAPTRECQL | |
| SCHEMBL8018140 | 0.80 | P2RX7 (0.36) | GAAP2RX7KDM4EPOLBMAPT | |
| SCHEMBL8005992 | 0.78 | KDM4E (0.35) | GAAP2RX7KDM4EPOLBMAPT | |
| SCHEMBL8703408 | 0.77 | MMP2 (0.34) | P2RX7KDM4EPOLBMAPTALDH1A1 | |
| SCHEMBL12885645 | 0.76 | KDM4E (0.40) | GAAP2RX7KDM4EPOLBMAPT | |
| Bicarbonate SCHEMBL8005998 | 0.76 | EPHX2 (0.35) | GAAP2RX7POLBEPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0773920-B1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 2000-01-26 | — | — | EP | disclosed |
| US-5808135-A | HERBICIDE; PESTICIDE | BAYER AKTIENGESELLSCHAFT (DE) | 1998-09-15 | — | — | US | disclosed |
| EP-0773920-A1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AG (DE) | 1997-05-21 | — | — | EP | disclosed |
| WO-1996003366-A1 | 2-(2,4,6-TRIMETHYL PHENYL)CYCLOPENTANE-1,3-DIONE DERIVATIVES | BAYER AKTIENGESELLSCHAFT (DE) | 1996-02-08 | — | — | WO | disclosed |