Thiram

Thiram

SCHEMBL80195

CN(C)C(=S)SSC(=S)N(C)C.CN(C)C(=S)SSC(=S)N(C)C.S

nearest known ligand 0.93

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.93
MGLL Q99685 8/20 0.93
ALDH2 P05091 5/20 0.93
LMNA P02545 3/20 0.93
HTT P42858 3/20 0.93
TP53 P04637 3/20 0.93
HPGD P15428 3/20 0.93
ALOX15 P16050 3/20 0.93
ALOX12 P18054 3/20 0.93
HSD17B10 Q99714 3/20 0.93
FAAH O00519 3/20 0.93
MAPT P10636 3/20 0.93
KMT2A Q03164 3/20 0.93
HSP90AA1 P07900 2/20 0.93
CYP3A4 P08684 2/20 0.93
FBP1 P09467 2/20 0.93
PKM P14618 2/20 0.93
LOX P28300 2/20 0.93
LOXL3 P58215 2/20 0.93
NPSR1 Q6W5P4 2/20 0.93

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiram SCHEMBL23248447 1.00 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL2773352 1.00 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL234787 1.00 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL9733279 0.97 MGLL (0.87) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL1246182 0.97 MGLL (0.87) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL21144 0.96 ALDH1A1 (1.00) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL1216571 0.96 ALDH1A1 (1.00) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL9516314 0.94 ALDH1A1 (0.81) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL6726644 0.94 ALDH1A1 (0.81) ALDH1A1MGLLALDH2LMNAHTT
Thiram SCHEMBL10881913 0.93 ALDH1A1 (0.93) ALDH1A1MGLLALDH2LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2142 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12539650-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-02-03 US claimed
EP-4408919-B1 SULFUR-CURABLE RUBBER COMPOSITION CONTAINING ORGANIC FILLERS AND ORGANOSILANE SUNCOAL IND GMBH (DE) 2025-10-29 EP claimed
EP-4514595-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2025-03-05 EP claimed
EP-4240578-B1 METHOD FOR MAKING PHOTOCHROMIC CONTACT LENSES ALCON INC (CH) 2024-12-18 EP claimed
US-20240392113-A1 SULFUR-CROSSLINKABLE RUBBER COMPOSITION CONTAINING ORGANIC FILLERS AND ORGANOSILANE SUNCOAL INDUSTRIES GMBH (DE) 2024-11-28 US claimed
CN-118930992-A Medical antibacterial nanometer butyronitrile glove and preparation method thereof 苏州益客医疗科技有限公司 2024-11-12 CN claimed
EP-4408919-A1 SULFUR-CROSSLINKABLE RUBBER COMPOSITION CONTAINING ORGANIC FILLERS AND ORGANOSILANE SunCoal Industries GmbH (DE) 2024-08-07 EP claimed
EP-3743469-B1 POLYMER BASED VULCANIZATION COMPOSITIONS AND METHOD FOR PREPARING THE COMPOSITIONS RUBBER NANO PRODUCTS PTY LIMITED (ZA) 2024-07-03 EP claimed
US-20240208128-A1 SYSTEM AND METHOD FOR CONTINUOUSLY MANUFACTURING CURED MEMBRANES AMRIZE TECHNOLOGY SWITZERLAND LLC (CH) 2024-06-27 US claimed
CN-118043393-A Rubber composition containing an organic filler and an organosilane that can be crosslinked by sulfur 森高工业有限公司 2024-05-14 CN claimed
US-4207196-A OXIDATION RESISTANCE, DIALKYL DITHIOCARBAMATE SALTS AND TETRAALKYL THIURAM SULFIDES FOR POLYOLEFINS THE B. F. GOODRICH COMPANY (US) 1980-06-10 US claimed
US-4129609-A Method for improving storage stability of epoxy ester thermosetting resins with thiuram compounds NIPPON SHOKUBAI KAGAKU KOGYO CO., LTD. (JP) 1978-12-12 US claimed
US-4085094-A SULFENYLTHIOCARBONATES THE GOODYEAR TIRE & RUBBER COMPANY (US) 1978-04-18 US claimed
US-4065443-A Vulcanization of rubber with phosphinothioyl amino sulfides MONSANTO COMPANY (US) 1977-12-27 US claimed
US-4062797-A DITHIOCARBAMATE AMERICAN CYANAMID COMPANY (US) 1977-12-13 US claimed
US-4042641-A Inhibiting premature vulcanization of rubbers with N-aryl-hydrocarbyldithio-formimidate THE GOODYEAR TIRE & RUBBER COMPANY (US) 1977-08-16 US claimed
US-4012332-A BENZOTHIAZOLE SULFENAMIDE, A THIURAM SULFIDE OR METAL DITHIOCARBAMATE, COPPER 2-MERCAPTOBENZOTHIAZOLE AMERICAN CYANAMID COMPANY (US) 1977-03-15 US claimed
US-3992448-A Chemical process for the preparation of thiuram monosulfides THE GOODYEAR TIRE & RUBBER COMPANY (US) 1976-11-16 US claimed
US-3992340-A Vulcanized molding compositions based on bitumen and olefin polymers BADISCHE ANILIN- & SODA-FABRIK AKTIENGESELLSCHAFT (DT) 1976-11-16 US claimed
US-3931090-A POLYISOPRENE, METAL OXIDE, ANTIOXIDANT, CURING XEROX CORPORATION (US) 1976-01-06 US claimed